36098-33-6
36098-33-6
Chemical Structure
F16
- CAS No.: 36098-33-6
- Formula:C16H15IN2
- Molecular Weight:362.21
IUPAC Name: (E)-4-(2-(1H-indol-3-yl)vinyl)-1-methylpyridin-1-ium iodide
InChIKey: UURAKYSOOXPORG-UHFFFAOYSA-N
SMILES: C[N+]1=CC=C(/C=C/C2=CNC3=C2C=CC=C3)C=C1.[I-]
Biological Activity:
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F16 | 99.94% | F16 is a potent growth inhibitor of the neu-overexpressing cells and also selectively inhibits proliferation of mammary epithelial as well as a variety of mouse mammary tumor and human breast cancer cell lines. | ||||||||||||||||||||
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F16 (Standard) | ≥98% | F16 (Standard) is the analytical standard of F16 (HY-100395). This product is intended for research and analytical applications. 0 | ||||||||||||||||||||
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References
- Fantin VR et al. A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth. Cancer Cell. 2002 Jul;2(1):29-42. [Content Brief]
- Fantin VR et al. F16, a mitochondriotoxic compound, triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell. Cancer Res. 2004 Jan 1;64(1):329-36. [Content Brief]
Keywords
