2. Apoptosis
  3. Apoptosis
  4. Anticancer agent 106

Anticancer agent 106 (compound 10ic) is an anticancer agent that induces apoptosis in B16-F10 melanoma cells. Anticancer agent 106 also potently inhibits metastatic nodules in a mouse model of lung metastatic melanoma. Anticancer agent 106 can be used in the study of cancer, especially lung metastatic melanoma.

For research use only. We do not sell to patients.

Anticancer agent 106 Chemical Structure

Anticancer agent 106 Chemical Structure

CAS No. : 3009090-13-2

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Anticancer agent 106 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Anticancer agent 106 (compound 10ic) is an anticancer agent that induces apoptosis in B16-F10 melanoma cells. Anticancer agent 106 also potently inhibits metastatic nodules in a mouse model of lung metastatic melanoma. Anticancer agent 106 can be used in the study of cancer, especially lung metastatic melanoma[1].

In Vitro

Anticancer agent 106 (compound 10ic; 0.28-55 μM; 24 h) reduces the viability of B16-F10 melanoma cells in a dose-dependent manner, with an IC50 value of 4.8 μM[1].
Anticancer agent 106 (5-20 μM; 48 h) induces apoptosis of B16-F10 melanoma cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 106 Related Antibodies

Cell Viability Assay[1]

Cell Line: B16-F10 melanoma cells
Concentration: 0.28-55 μM
Incubation Time: 24 h
Result: Inhibited B16-F10 melanoma cells in a dose-dependent manner (IC50 = 4.8 μM).

Apoptosis Analysis[1]

Cell Line: B16-F10 melanoma cells
Concentration: 5-20 μM
Incubation Time: 48 h
Result: Induced cell apoptosis.
In Vivo

Anticancer agent 106 (9-9.5 mg/kg; i.p.; every 3rd d for 22 d) inhibits the metastatic nodules in pulmonary metastatic melanoma mouse model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: B16-F10 melanoma-bearing C57BL/6 mice (pulmonary metastatic melanoma model)[1].
Dosage: 9-9.5 mg/kg
Administration: Intraperitoneal administration; every 3rd d for 22 d.
Result: Inhibited the lung metastases.
Molecular Weight

475.56

Formula

C26H25N3O4S
CAS No.
SMILES

N#CC1=C(N)N(C2=C(C(OCC)=O)C(CCCCC3)=C3S2)/C(C1=O)=C/C(C4=CC=C(C)C=C4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Anticancer agent 106 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 1063009090-13-2Anticancer agent106Anticancer agent-106Apoptosiscancerlung metastatic melanomamelanomaB16-F10 cellsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Anticancer agent 106
Cat. No.:
HY-149950
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.