1. GPCR/G Protein MAPK/ERK Pathway
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  3. KRAS G12C inhibitor 16

KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 39, has an IC50 of 97 nM.

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KRAS G12C inhibitor 16 Chemical Structure

KRAS G12C inhibitor 16 Chemical Structure

CAS No. : 2349392-79-4

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Description

KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 39, has an IC50 of 97 nM[1].

IC50 & Target[1]

KRas G12C

97 nM (IC50)

Molecular Weight

453.89

Formula

C24H21ClFN3O3

CAS No.
SMILES

OC1=C(C2=C(C)C(N=CC3=C4N5[C@H](CN(C(C=C)=O)CC5)CO3)=C4C=C2Cl)C(F)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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KRAS G12C inhibitor 16 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KRAS G12C inhibitor 16
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HY-125874
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