Anti-Mouse CD16.2 Antibody (9E9)
Based on 1 Customer Validation
Anti-Mouse CD16.2 Antibody (9E9) is a Armenian hamster-derived IgG type antibody inhibitor, targeting to mouse CD16.2. Anti-Mouse CD16.2 Antibody (9E9) reacts with mouse CD16.2, also known as FcγRIV (Fc receptor, IgG, low affinity IV). Anti-Mouse CD16.2 Antibody (9E9) inhibits cellular CD16.2 expression and signaling and blocks FcγRIV. Anti-Mouse CD16.2 Antibody (9E9) can be used for the researches of cancer, inflammation and immunology, such as CT26 tumor and lung inflammation.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 95%
- Peso molecular:150 kDa
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
Isotype
Armenian hamster IgG
Recommend Isotype Controls
Species Reactivity
Mouse
In Vitro
In Vivo
Anti-Mouse CD16.2 Antibody (9E9) (200 μg, i.p., atdays 0. 4. 8) reduces cutaneous lesions in bullous pemphigoid mice[2].
Anti-Mouse CD16.2 Antibody (9E9) (200 μg, i.v., 1 hour prior to injection of anti-CTLA4) prevents anti-CTLA4-mediatied depletion of Tregs in CT26 tumor mice[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Product Image
Aplicación
in vivo CD16.2 blockade; in vitro CD16.2 blockade; Flow cytometry
Chemical Information
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Appearance Liquid
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Peso molecular 150 kDa
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Color Colorless to off-white
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SMILES
[Anti-Mouse CD16.2 Antibody (9E9)]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (258 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
[1]. Mancardi DA, et al. FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammation. J Clin Invest. 2008 Nov;118(11):3738-50. [Content Brief]
[2]. Schulze FS, et al. Fcγ receptors III and IV mediate tissue destruction in a novel adult mouse model of bullous pemphigoid. Am J Pathol. 2014 Aug;184(8):2185-96. [Content Brief]
[3]. Sanseviero E, et al. Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control. Cancer Immunol Res. 2019 Aug;7(8):1371-1380. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-Mouse CD16.2 Antibody (9E9) Related Classifications
HY-P990291 Related Classifications
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