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Cat. No.: HY-P990291

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Anti-Mouse CD16.2 Antibody (9E9)

Name: Anti-Mouse CD16.2 Antibody (9E9)
Brand: MedChemExpress
SKU: HY-P990291
Price: 220.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

Anti-Mouse CD16.2 Antibody (9E9) is a Armenian hamster-derived IgG type antibody inhibitor, targeting to mouse CD16.2. Anti-Mouse CD16.2 Antibody (9E9) reacts with mouse CD16.2, also known as FcγRIV (Fc receptor, IgG, low affinity IV). Anti-Mouse CD16.2 Antibody (9E9) inhibits cellular CD16.2 expression and signaling and blocks FcγRIV. Anti-Mouse CD16.2 Antibody (9E9) can be used for the researches of cancer, inflammation and immunology, such as CT26 tumor and lung inflammation.

For research use only. We do not sell to patients.

Purity: 95%
Molecular Weight:150 kDa

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Anti-Mouse CD16.2 Antibody (9E9) Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- In Vitro
- In Vivo
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Isotype

Armenian hamster IgG

Recommend Isotype Controls

Polyclonal Armenian hamster IgG, Isotype Control

Species Reactivity

Mouse

In Vitro

Anti-Mouse CD16.2 Antibody (9E9) (10 μg/mL) abrogates IgE IC–induced TNF-α secretion in MH-S cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Anti-Mouse CD16.2 Antibody (9E9) (i.v., 1 day before recovery of thioglycolate-elicited macrophages) inhibits 25% of TNF-α secretion by macrophages in hFcεRI^Tg mice^[1].
Anti-Mouse CD16.2 Antibody (9E9) (200 μg, i.p., atdays 0. 4. 8) reduces cutaneous lesions in bullous pemphigoid mice^[2].
Anti-Mouse CD16.2 Antibody (9E9) (200 μg, i.v., 1 hour prior to injection of anti-CTLA4) prevents anti-CTLA4-mediatied depletion of Tregs in CT26 tumor mice^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

Product Image

Application

in vivo CD16.2 blockade; in vitro CD16.2 blockade; Flow cytometry

Chemical Information

Appearance Liquid
Molecular Weight 150 kDa
Color Colorless to off-white
SMILES

[Anti-Mouse CD16.2 Antibody (9E9)]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

References

[1]. Mancardi DA, et al. FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammation. J Clin Invest. 2008 Nov;118(11):3738-50. [Content Brief]

[2]. Schulze FS, et al. Fcγ receptors III and IV mediate tissue destruction in a novel adult mouse model of bullous pemphigoid. Am J Pathol. 2014 Aug;184(8):2185-96. [Content Brief]

[3]. Sanseviero E, et al. Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Rα Complexes Enhances Tumor Control. Cancer Immunol Res. 2019 Aug;7(8):1371-1380. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- In Vitro
- In Vivo
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

Anti-Mouse CD16.2 Antibody (9E9)

HOLO Human Interleukin-2 (IL-2) Detection Kit

Bradford Protein Assay Kit

Protein A Agarose

Cell-ATP Viability Detection Kit

PBS Buffer (1×)

Cytotoxicity LDH Assay Kit

DPBS Buffer (1×)