1. Apoptosis
  2. RIP kinase
  3. RIPK1-IN-12

RIPK1-IN-12 

Cat. No.: HY-144277
Handling Instructions

RIPK1-IN-12 is a potent RIPK1 inhibitor. RIPK1-IN-12 inhibits necroptosis in both human and mouse cells, with EC50 values of 1.6 and 2.9 nM, respectively.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

RIPK1-IN-12 Chemical Structure

RIPK1-IN-12 Chemical Structure

CAS No. : 2173556-92-6

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Description

RIPK1-IN-12 is a potent RIPK1 inhibitor. RIPK1-IN-12 inhibits necroptosis in both human and mouse cells, with EC50 values of 1.6 and 2.9 nM, respectively[1].

IC50 & Target

RIPK1[1]

In Vitro

RIPK1-IN-12 (Compound 58; 24 hours) demonstrates potent anti-necroptotic activity (EC50=1.6 nM in HT-29 cells and EC50= 2.9 nM in L929 cells)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

450.55

Formula

C24H26N4O3S

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
RIPK1-IN-12
Cat. No.:
HY-144277
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