COX-1/2-IN-4
COX-1/2-IN-4 (compound 2b) is anCOX inhibitorwith IC50 values of 0.239 μM and 0.191 μM for COX-1 enzyme and COX-2 enzyme , respectively. COX-1/2-IN-4showsmoderateanticanceractivity against COLO205 and B16F1 cancer cell lines with IC50 values of 30.79 and 74.15 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2967296-91-7
- Formula: C22H24N2O2S
- Molecular Weight:380.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50= 0.239 μM (COX-1 enzyme); IC50= 0.191 μM (COX-2 enzyme)[1]
Chemical Information
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CAS No. 2967296-91-7
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Molecular Weight 380.50
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Formula C22H24N2O2S
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SMILES
CC(C)(C)C(C=C1)=CC=C1NC(C(S2)=C(N=C2C3=CC=CC(OC)=C3)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)