2. Immunology/Inflammation
  3. COX
  4. COX-1/2-IN-4

COX-1/2-IN-4 (compound 2b) is anCOX inhibitorwith IC50 values of 0.239 μM and 0.191 μM for COX-1 enzyme and COX-2 enzyme , respectively. COX-1/2-IN-4showsmoderateanticanceractivity against COLO205 and B16F1 cancer cell lines with IC50 values of 30.79 and 74.15 μM, respectively.

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COX-1/2-IN-4 Chemical Structure

COX-1/2-IN-4 Chemical Structure

CAS No. : 2967296-91-7

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COX-1/2-IN-4 Related Antibodies

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Description

COX-1/2-IN-4 (compound 2b) is anCOX inhibitorwith IC50 values of 0.239 μM and 0.191 μM for COX-1 enzyme and COX-2 enzyme , respectively. COX-1/2-IN-4showsmoderateanticanceractivity against COLO205 and B16F1 cancer cell lines with IC50 values of 30.79 and 74.15 μM, respectively[1].

IC50 & Target

IC50= 0.239 μM (COX-1 enzyme); IC50= 0.191 μM (COX-2 enzyme)[1]
Molecular Weight

380.50

Formula

C22H24N2O2S
CAS No.
SMILES

CC(C)(C)C(C=C1)=CC=C1NC(C(S2)=C(N=C2C3=CC=CC(OC)=C3)C)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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COX-1/2-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COX-1/2-IN-42967296-91-7COXCyclooxygenaseCOX InhibitorInhibitorinhibitorinhibit

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