2967296-91-7
2967296-91-7
Chemical Structure
COX-1/2-IN-4
- CAS No.: 2967296-91-7
- Formula:C22H24N2O2S
- Molecular Weight:380.50
InChIKey: LVWLJRCNLLCLBW-UHFFFAOYSA-N
SMILES: CC(C)(C)C(C=C1)=CC=C1NC(C(S2)=C(N=C2C3=CC=CC(OC)=C3)C)=O
Biological Activity: COX-1/2-IN-4 (compound 2b) is anCOX inhibitorwith IC50 values of 0.239 μM and 0.191 μM for COX-1 enzyme and COX-2 enzyme , respectively. COX-1/2-IN-4showsmoderateanticanceractivity against COLO205 and B16F1 cancer cell lines with IC50 values of 30.79 and 74.15 μM, respectively[1].
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COX-1/2-IN-4 | COX-1/2-IN-4 (compound 2b) is anCOX inhibitorwith IC50 values of 0.239 μM and 0.191 μM for COX-1 enzyme and COX-2 enzyme , respectively. COX-1/2-IN-4showsmoderateanticanceractivity against COLO205 and B16F1 cancer cell lines with IC50 values of 30.79 and 74.15 μM, respectively. | |||||||||||||||||||||
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References
Keywords
