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Art. -Nr.: HY-157481

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HDAC1-IN-6

HDAC1-IN-6 (compound 1) is an inhibitor of HDAC1 and 11, with an IC₅₀ of 1.9 μM and 1.6 μM, respectively. HDAC1-IN-6 induces differentiation in AML cells.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₃H₂₆N₆O
Molecular Weight:402.49

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

HDAC1-IN-6 Chemical Structure

Größe

Preis

Verfügbarkeit

Menge

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

HDAC1-IN-6 (compound 1) is an inhibitor of HDAC1 and 11, with an IC₅₀ of 1.9 μM and 1.6 μM, respectively. HDAC1-IN-6 induces differentiation in AML cells^[1].

IC₅₀ & Target

HDAC11

1.6±0.3 μM (IC₅₀)

HDAC1

1.9±0.3 μM (IC₅₀)

HDAC2

>30 μM (IC₅₀)

HDAC6

>30 μM (IC₅₀)

Alle HDAC Isoform-spezifische Produkte anzeigen :

Chemical Information

Molecular Weight 402.49
Formel C₂₃H₂₆N₆O
SMILES

O=C(NC1=C(N)C=CC=C1)[C@@H]2CC[C@H](CC2)CNC3=NC=CC(C4=CC=CN=C4)=N3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Purnima Kumar, et al. HDAC inhibitor derivatives induce differentiation of leukemic cells through two distinct and separable mechanisms.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise

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Art. -Nr.:
Menge:
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CAS. Nr.:
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Reinheit:
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HDAC1-IN-6

Alle HDAC Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

HDAC1-IN-6 Related Classifications

HY-157481 Related Classifications

Bioz

Keywords

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