Desmethyl-YM-298198 hydrochloride
Desmethyl-YM-298198 hydrochloride is a high-affinity, selective, and noncompetitive mGluR1 antagonist (IC50: 16 nM). Desmethyl-YM-298198 hydrochloride has analgesic effect in Streptozotocin (HY-13753)-induced hyperalgesic mice.
For research use only. We do not sell to patients.
- CAS No.: 1177767-57-5
- Formula: C17H21ClN4OS
- Molecular Weight:364.89
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
16 nM (mGluR1)[1]
Chemical Information
-
CAS No. 1177767-57-5
-
Molecular Weight 364.89
-
Formula C17H21ClN4OS
-
SMILES
O=C(C1=C(C)N2C3=CC(N)=CC=C3N=C2S1)NC4CCCCC4.[H]Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kohara A, et al. Radioligand binding properties and pharmacological characterization of 6-amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective, and noncompetitive antagonist of metabotropic glutamate receptor type 1. J Pharmacol Exp Ther. 2005 Oct;315(1):163-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Desmethyl-YM-298198 hydrochloride Related Classifications
HY-103567 Related Classifications
Powered by Bioz