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Cat. No.: HY-163398

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TLR7-IN-1

TLR7-IN-1 (Compound 16-A) is a TLR7 agonist with an EC₅₀ of 0.001 μM. TLR7-IN-1 is applicable to cancer-related research.

For research use only. We do not sell to patients.

CAS No.: 3026308-79-9
Formula: C₁₈H₂₆N₇O₃P
Molecular Weight:419.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

TLR7-IN-1 Chemical Structure

CAS No.: 3026308-79-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

TLR7-IN-1 (Compound 16-A) is a TLR7 agonist with an EC₅₀ of 0.001 μM. TLR7-IN-1 is applicable to cancer-related research^[1].

IC₅₀ & Target^[1]

TLR7

0.001 μM (IC₅₀)

All Toll-like Receptor (TLR) Isoforms :

In Vitro

TLR7-IN-1 potently activates TLR7 in HEK293-Blue-hTLR7 cells, with an EC₅₀ of 0.001 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3026308-79-9
Molecular Weight 419.42
Formula C₁₈H₂₆N₇O₃P
SMILES

O=C1N(C2=NC([P@](CC)(C)=O)=NC(N)=C2N1)CC(C=C3)=CN=C3OCCN(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chungen Liang, et al. Phosphorylpurinone compounds for the treatment of cancer. WO2024013205A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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TLR7-IN-1

All Toll-like Receptor (TLR) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

TLR7-IN-1 Related Classifications

HY-163398 Related Classifications