16,16-Dimethylprostaglandin E1
16,16-Dimethylprostaglandin E1 (16,16-dimethyl-PGE1) is a PGE1 (HY-B0131) analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation.
For research use only. We do not sell to patients.
- CAS No.: 41692-15-3
- Formula: C22H38O5
- Molecular Weight:382.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague-Dawley rats[1]
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Dosage:1 μg/kg•min
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Administration:0-30 min
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Result:Improved blood pressure and heart rate, improved levels of epinephrine and norepinephrine im plasma.
Chemical Information
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CAS No. 41692-15-3
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Molecular Weight 382.53
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Formula C22H38O5
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SMILES
CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O
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Synonyms
16,16-dimethyl-PGE1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Feuerstein G, et al., Prostaglandins, catecholamines, and cardiovascular responses to hemorrhage. Am J Physiol. 1981 Mar;240(3):R166-74. [Content Brief]
[2]. Jumblatt MM, et al., Prostaglandin E2 effects on corneal endothelial cyclic adenosine monophosphate synthesis and cell shape are mediated by a receptor of the EP2 subtype. Invest Ophthalmol Vis Sci. 1991 Feb;32(2):360-5. [Content Brief]
[3]. Strandberg K, et al., Bronchial effects of some prostaglandin E and F analogues. Acta Physiol Scand. 1977 Jun;100(2):172-81. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
16,16-Dimethylprostaglandin E1 Related Classifications
HY-114751 Related Classifications
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