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  3. 16,16-Dimethylprostaglandin E1

16,16-Dimethylprostaglandin E1  (Synonyms: 16,16-dimethyl-PGE1)

Cat. No.: HY-114751
Handling Instructions

16,16-Dimethylprostaglandin E1 (16,16-dimethyl-PGE1) is a PGE1 (HY-B0131) analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation.

For research use only. We do not sell to patients.

16,16-Dimethylprostaglandin E1 Chemical Structure

16,16-Dimethylprostaglandin E1 Chemical Structure

CAS No. : 41692-15-3

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Description

16,16-Dimethylprostaglandin E1 (16,16-dimethyl-PGE1) is a PGE1 (HY-B0131) analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation[1][2][3].

In Vivo

16,16-Dimethylprostaglandin E1 (1 μg/kg•min for 30 min) accelerates blood pressure and heart rate recovery rate, increases catecholamine turnover, enhances levels of epinephrine and norepinephrine in plasma following acute hemorrhage in Sprague Dawley rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley rats[1]
Dosage: 1 μg/kg•min
Administration: 0-30 min
Result: Improved blood pressure and heart rate, improved levels of epinephrine and norepinephrine im plasma.
Molecular Weight

382.53

Formula

C22H38O5

CAS No.
SMILES

CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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16,16-Dimethylprostaglandin E1 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
16,16-Dimethylprostaglandin E1
Cat. No.:
HY-114751
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