41692-15-3
41692-15-3
Chemical Structure
16,16-Dimethylprostaglandin E1
Synonym(s): 16,16-dimethyl-PGE1
- CAS No.: 41692-15-3
- Formula:C22H38O5
- Molecular Weight:382.53
IUPAC Name: 7-((1R,2R,3R)-3-hydroxy-2-((R,E)-3-hydroxy-4,4-dimethyloct-1-en-1-yl)-5-oxocyclopentyl)heptanoic acid
InChIKey: RQOFITYRYPQNLL-ZWSAOQBFSA-N
SMILES: CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O
Biological Activity: 16,16-Dimethylprostaglandin E1 (16,16-dimethyl-PGE1) is a PGE1 (HY-B0131) analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation[1][2][3].
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16,16-Dimethylprostaglandin E1 | 16,16-Dimethylprostaglandin E1 (16,16-dimethyl-PGE1) is a PGE1 (HY-B0131) analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation. | |||||||||||||||||||||
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References
- [1]. Feuerstein G, et al., Prostaglandins, catecholamines, and cardiovascular responses to hemorrhage. Am J Physiol. 1981 Mar;240(3):R166-74. [Content Brief]
- [2]. Jumblatt MM, et al., Prostaglandin E2 effects on corneal endothelial cyclic adenosine monophosphate synthesis and cell shape are mediated by a receptor of the EP2 subtype. Invest Ophthalmol Vis Sci. 1991 Feb;32(2):360-5. [Content Brief]
- [3]. Strandberg K, et al., Bronchial effects of some prostaglandin E and F analogues. Acta Physiol Scand. 1977 Jun;100(2):172-81. [Content Brief]
Keywords
