country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-143426

Copy Link Print Information

MALT1-IN-8

MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC₅₀ of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC₅₀ of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2244109-29-1
화학식: C₂₀H₁₅Cl₂N₇O
분자량:440.29

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

MALT1-IN-8 Chemical Structure

CAS No.: 2244109-29-1

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

IC50: 2 nM (MALT1 protease)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
OCI-Ly3	EC₅₀	0.99 μM Compound: 15	Antiproliferative activity against human OCILY3 cells by cell proliferation assay Antiproliferative activity against human OCILY3 cells by cell proliferation assay	[PMID: 31129051]

Chemical Information

CAS No. 2244109-29-1
분자량 440.29
화학식 C₂₀H₁₅Cl₂N₇O
SMILES

O=C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)NC3=C(C4CC4)C5=CC(Cl)=CC=C5N=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nathanael S. Gray, et al. Inhibitors of malt1 and uses thereof. WO2018165385A1.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기