MALT1-IN-8
MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC50 of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC50 of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8).
For research use only. We do not sell to patients.
- CAS No.: 2244109-29-1
- Formula: C20H15Cl2N7O
- Molecular Weight:440.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 2 nM (MALT1 protease)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| OCI-Ly3 | EC50 |
0.99 μM
Compound: 15
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Antiproliferative activity against human OCILY3 cells by cell proliferation assay
Antiproliferative activity against human OCILY3 cells by cell proliferation assay
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[PMID: 31129051] |
Chemical Information
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CAS No. 2244109-29-1
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Molecular Weight 440.29
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Formula C20H15Cl2N7O
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SMILES
O=C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)NC3=C(C4CC4)C5=CC(Cl)=CC=C5N=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MALT1-IN-8 Related Classifications
HY-143426 Related Classifications
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