2244109-29-1
2244109-29-1
Chemical Structure
MALT1-IN-8
- CAS No.: 2244109-29-1
- Formula:C20H15Cl2N7O
- Molecular Weight:440.29
IUPAC Name: 1-(6-chloro-4-cyclopropylquinolin-3-yl)-3-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-yl)urea
InChIKey: JROMLJWGZZEFRO-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)NC3=C(C4CC4)C5=CC(Cl)=CC=C5N=C3
Biological Activity: MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC50 of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC50 of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8)[1].
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MALT1-IN-8 | MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC50 of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC50 of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8). | |||||||||||||||||||||
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