IL-16 Protein, Human (His)
IL-16 Protein, a cytokine, regulates immunity and inflammation. It controls the activation and movement of immune cells like T cells and monocytes. Understanding IL-16 Protein's functions helps study immune responses and develop treatments for inflammatory and autoimmune disorders. IL-16 Protein, Human (His) is the recombinant human-derived IL-16 protein, expressed by E. coli , with N-His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
IL-16 Protein, a cytokine, regulates immunity and inflammation. It controls the activation and movement of immune cells like T cells and monocytes. Understanding IL-16 Protein's functions helps study immune responses and develop treatments for inflammatory and autoimmune disorders. IL-16 Protein, Human (His) is the recombinant human-derived IL-16 protein, expressed by E. coli , with N-His labeled tag.
IL-16, a multifunctional cytokine, elicits a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Additionally, it primes CD4+ T-cells for responsiveness to IL-2 and IL-15, and induces the expression of interleukin-2 receptor in T-lymphocytes. Functioning as a ligand for CD4, IL-16 plays a key role in cellular interactions and immune modulation. Beyond its immunomodulatory functions, IL-16 may serve as a scaffolding protein that anchors ion channels in the cell membrane, contributing to its diverse cellular effects.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-His
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Accession
AAC12732.1 (P2-S130)
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Molecular Construction
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N-term
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His
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IL-16 (P2-S130)
Accession # AAC12732.1 -
C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
IL16; FLJ42735; Interleukin 16; FLJ16806; Pro-Interleukin-16; IL-16; PrIL-16; Interleukin 16 (Lymphocyte Chemoattractant Factor); LCF; Neuronal Interleukin 16; Lymphocyte Chemoattractant Factor; IL16 Protein; Prointerleukin 16; PRIL16; HsT19289; NIL16
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AA Sequence
PDLNSSTDSAASASAASDVSVESTAEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTAAGDS
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Predicted Molecular Mass
15.3 kDa
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Molecular Weight
Approximately 24 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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