1. Anti-infection
  2. SARS-CoV
    Virus Protease
  3. Mpro inhibitor N3 hemihydrate

Mpro inhibitor N3 hemihydrate 

Cat. No.: HY-136149A Purity: ≥98.0%
Handling Instructions

Mpro inhibitor N3 hemihydrate is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 of 16.77 μM for SARS-CoV-2. Mpro inhibitor N3 hemihydrate specifically inhibits Mpro from multiple coronaviruses, including SARS-CoV and MERS-CoV. Mpro inhibitor N3 hemihydrate displays inhibition against HCoV-229E, FIPV, and MHV-A59 with individual IC50 of 4.0 μM, 8.8 μM, and 2.7 μM, respectively.

For research use only. We do not sell to patients.

Mpro inhibitor N3 hemihydrate Chemical Structure

Mpro inhibitor N3 hemihydrate Chemical Structure

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Description

Mpro inhibitor N3 hemihydrate is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 of 16.77 μM for SARS-CoV-2. Mpro inhibitor N3 hemihydrate specifically inhibits Mpro from multiple coronaviruses, including SARS-CoV and MERS-CoV. Mpro inhibitor N3 hemihydrate displays inhibition against HCoV-229E, FIPV, and MHV-A59 with individual IC50 of 4.0 μM, 8.8 μM, and 2.7 μM, respectively[1][2].

IC50 & Target

EC50: 16.77 μM (SARS-CoV-2)[1]

In Vivo

Mpro inhibitor N3 hemihydrate (0-0.64 μM) is able to penetrate cells to inhibit the replication of IBV viruses, probably at the beginning of infection in embryos[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

698.81

Formula

C₃₅H₅₀N₆O₉

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
References

Purity: ≥98.0%

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Product Name:
Mpro inhibitor N3 hemihydrate
Cat. No.:
HY-136149A
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