country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-153570

Copy Link Print Information

Influenza virus-IN-7

Influenza virus-IN-7 (Example 16) is an orally active cap-dependent endonuclease inhibitor that can be used for the research of influenza viral infectious diseases.

For research use only. We do not sell to patients.

CAS No.: 2703046-92-6
Formula: C₂₉H₂₆F₂N₄O₇S
Molecular Weight:612.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Influenza virus-IN-7 Chemical Structure

CAS No.: 2703046-92-6

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Influenza virus-IN-7 (Example 16) is an orally active cap-dependent endonuclease inhibitor that can be used for the research of influenza viral infectious diseases^[1].

IC₅₀ & Target

IC50: Cap-dependent endonuclease^[1]

In Vitro

Influenza virus-IN-7 (Example 16) shows antiviral activity against influenza A/Weiss/43(H1N1) virus with an EC₅₀ of <5 nM in MDCK cells (CC₅₀ >1000 nM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Influenza virus-IN-7 (Example 16; 5 mg/kg; i.g.; twice daily for 5 days) improves the survival rate in WSN/33 (H1N1) infection mouse model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

WSN/33 (H1N1) infection mouse model^[1]
Dosage:

5 mg/kg
Administration:

Intragastric administration, twice daily for 5 days
Result:

Significantly improved the survival rate.

Chemical Information

CAS No. 2703046-92-6
Molecular Weight 612.60
Formula C₂₉H₂₆F₂N₄O₇S
SMILES

O=C1C(N(C=C2)N([C@H]3C4=CC=C(F)C(F)=C4CSC5=CC=CC=C53)[C@@]6([H])N1CC/C(C6)=N\OC)=C(OCOC(OC)=O)C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang Shen, et al. Polycyclic pyridopyridazine amide oxime-containing carbocyclic derivatives and uses thereof. Patent CN114315827A.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote