C18:1-Ceramide-13C18
Based on 1 Customer Validation
C18:1-Ceramide-13C18 is the 13C-labeled C18:1-Ceramide (HY-141578). C18:1-Ceramide is a ceramide subspecies belonging to bioactive lipids. C18:1-Ceramide exhibits activities of inducing skeletal muscle insulin resistance and affecting metabolism. C18:1-Ceramide can be used in the research of obesity, type 2 diabetes (T2D), insulin resistance and other related metabolic diseases.
For research use only. We do not sell to patients.
- Assay : 97.0%
- Formula: C1813C18H69NO3
- Molecular Weight:581.81
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All Endogenous Metabolite Isoforms
More
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 5966-28-9
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Appearance Solid
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Molecular Weight 581.81
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Formula C1813C18H69NO3
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Color White to off-white
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SMILES
[13CH3][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2]/[13CH]=[13CH]\[13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13CH2][13C](N[C@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)CO)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMF : 100 mg/mL (171.88 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 1.7188 mL | 8.5939 mL | 17.1877 mL | 42.9694 mL |
| 5 mM | 0.3438 mL | 1.7188 mL | 3.4375 mL | 8.5939 mL | |
| 10 mM | 0.1719 mL | 0.8594 mL | 1.7188 mL | 4.2969 mL | |
| 15 mM | 0.1146 mL | 0.5729 mL | 1.1458 mL | 2.8646 mL | |
| 20 mM | 0.0859 mL | 0.4297 mL | 0.8594 mL | 2.1485 mL | |
| 25 mM | 0.0688 mL | 0.3438 mL | 0.6875 mL | 1.7188 mL | |
| 30 mM | 0.0573 mL | 0.2865 mL | 0.5729 mL | 1.4323 mL | |
| 40 mM | 0.0430 mL | 0.2148 mL | 0.4297 mL | 1.0742 mL | |
| 50 mM | 0.0344 mL | 0.1719 mL | 0.3438 mL | 0.8594 mL | |
| 60 mM | 0.0286 mL | 0.1432 mL | 0.2865 mL | 0.7162 mL | |
| 80 mM | 0.0215 mL | 0.1074 mL | 0.2148 mL | 0.5371 mL | |
| 100 mM | 0.0172 mL | 0.0859 mL | 0.1719 mL | 0.4297 mL |
Keywords
- C18:1-Ceramide-13C18
- Isotope-Labeled Compounds
- Endogenous Metabolite
- mouse blood mononuclear cells
- murine immune cells
- human L02 hepatocytes
- alkaline ceramidase 3
- colonic epithelial cells
- primary peritoneal macrophages
- Acer3-deficient mouse primary hepatocytes
- DSS-induced colitis
- skeletal muscle insulin resistance
- colon tissues
- Inhibitor
- inhibitor
- inhibit