Isotope-Labeled Ceramides

C16-Ceramide-d₉ is deuterium labeled C16-Ceramide.

C18-Ceramide-d₇ is deuterium labeled C18-Ceramide.

C16-Ceramide-d₃₁ is deuterium labeled C16-Ceramide.

C18:1-Ceramide-¹³C₁₈ is the ¹³C-labeled C18:1-Ceramide (HY-141578). C18:1-Ceramide is a ceramide subspecies belonging to bioactive lipids. C18:1-Ceramide exhibits activities of inducing skeletal muscle insulin resistance and affecting metabolism. C18:1-Ceramide can be used in the research of obesity, type 2 diabetes (T2D), insulin resistance and other related metabolic diseases.

C24:1-Ceramide-d₇ is the deuterium labeled C24:1-Ceramide.

Ceramide C6-d₇ is the deuterium labeled Ceramide C6. Ceramide C6, a Ceramide pathway activator, is an exogenous short-chain ceramide which can induce apoptosis of multiple cancer cells.

C6 Ceramide-d₁₁ is deuterated labeled C6 Ceramide (HY-19542). C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects.

C14 Ceramide (d18:1/14:0)-d₇ is the deuterium labeled C14 Ceramide (d18:1/14:0) (HY-124177A). C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research.

C18 Dihydroceramide-d₃ is deuterium labeled C18 Dihydroceramide. C18 Dihydroceramide is an ester product.

C16 Ceramide-d₇ (d16:1,C16:0) is the deuterium labeled C16 Ceramide (d16:1,C16:0).

C24-Ceramide-d₇ is the deuterium labeled C24-Ceramide.

CER3-d₉ is deuterium labeled CER3.

CER10-d₉ is deuterium labeled CER10.

C18 Dihydroceramide-d₃-1 (N-octadecaoyl-D-eytho-Dihydosphigosie-d₃) is deuterium labeled C18 Dihydroceramide. C18 Dihydroceramide is an ester product.

C18-Ceramide-13C2,d2 is a deuterated labeled C18-Ceramide-13C2,d2.

Ceramide 3-d₃ (N-Stearoyl phytosphingosine-d₃) is deuterium labeled Ceramide 3. Ceramide 3 is an orally active major component of intercellular lipids in the stratum corneum of the skin, and belongs to the ceramide family. Ceramide 3 inhibits c-jun and NF-κB activation induced by Histamine (HY-B1204), and suppresses the expression of IL-4 and TNF-α. Ceramide 3 inhibits scratching behavior and vascular permeability in mice, and exhibits antihistamine effects in guinea pig ileum. Ceramide 3 improves skin barrier function, reduces transepidermal water loss, erythema and the number of circulating epidermal cells, and accelerates barrier repair of irritated or dysfunctional skin.

C15-Ceramide-d₇ is deuterium labeled C15-Ceramide. C15-Ceramide is an ester product.

C18 Ceramide-1-phosphate (d18:1/18:0)-d₃ is the deuterium labeled C18 Ceramide-1-phosphate (d18:1/18:0) (HY-160850). C18 Ceramide-1-phosphate (d18:1/18:0) is a specific type of long-chain molecule found in murine skin. C18 Ceramide-1-phosphate (d18:1/18:0) promotes migration of both mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells at concentrations between 0.5-5 μM. C18 Ceramide-1-phosphate (d18:1/18:0)’s levels are higher in CFPAC-1 pancreatic ductal adenocarcinoma cells than in pancreatic cancer stem cells.

C15 Ceramide-1-phosphate-d₇ is deuterium labeled C15 Ceramide-1-phosphate.

CER1 (d18:1/26:0/18:1)-d₉ is deuterium labeled CER1 (d18:1/26:0/18:1).