5966-28-9
5966-28-9
Chemical Structure
C18:1-Ceramide
- CAS No.: 5966-28-9
- Formula:C36H69NO3
- Molecular Weight:563.94
IUPAC Name: N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)oleamide
InChIKey: OBFSLMQLPNKVRW-RHPAUOISSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)=O
Biological Activity: C18:1-Ceramide is a ceramide subspecies belonging to bioactive lipids. C18:1-Ceramide exhibits activities of inducing skeletal muscle insulin resistance and affecting metabolism. C18:1-Ceramide can be used in the research of obesity, type 2 diabetes (T2D), insulin resistance and other related metabolic diseases[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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C18:1-Ceramide | 99.93% | C18:1-Ceramide is a ceramide subspecies belonging to bioactive lipids. C18:1-Ceramide exhibits activities of inducing skeletal muscle insulin resistance and affecting metabolism. C18:1-Ceramide can be used in the research of obesity, type 2 diabetes (T2D), insulin resistance and other related metabolic diseases. | ||||||||||||||||||||
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C18:1-Ceramide (Standard) | ≥98% | C18:1-Ceramide (Standard) is the analytical standard of C18:1-Ceramide (HY-141578). This product is intended for research and analytical applications. C18:1-Ceramide is a ceramide subspecies belonging to bioactive lipids. C18:1-Ceramide exhibits activities of inducing skeletal muscle insulin resistance and affecting metabolism. C18:1-Ceramide can be used in the research of obesity, type 2 diabetes (T2D), insulin resistance and other related metabolic diseases. | ||||||||||||||||||||
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C18:1 Ceramide-d7 | C18:1 Ceramide-d7 is the deuterated-labeled C18:1-Ceramide (HY-141578). C18:1-Ceramide is a ceramide subspecies belonging to bioactive lipids. C18:1-Ceramide exhibits activities of inducing skeletal muscle insulin resistance and affecting metabolism. C18:1-Ceramide can be used in the research of obesity, type 2 diabetes (T2D), insulin resistance and other related metabolic diseases. | |||||||||||||||||||||
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C18:1-Ceramide-13C18 | 97.0% | C18:1-Ceramide-13C18 is the 13C-labeled C18:1-Ceramide (HY-141578). C18:1-Ceramide is a ceramide subspecies belonging to bioactive lipids. C18:1-Ceramide exhibits activities of inducing skeletal muscle insulin resistance and affecting metabolism. C18:1-Ceramide can be used in the research of obesity, type 2 diabetes (T2D), insulin resistance and other related metabolic diseases. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.94
HY-179792C16:0 Ceramide (d18:2(4E,8Z)/16:0) -
Similarity Score 0.93
HY-179806C24:1 Ceramide (d17:1/24:1(15Z)) -
Similarity Score 0.92
HY-134575C24:1-Ceramide -
Similarity Score 0.91
HY-179807C24:1 Ceramide (d18:2(4E,8Z)/24:1(15Z)) -
Similarity Score 0.91
HY-116258C16 Ceramide (d16:1,C16:0) -
Similarity Score 0.91
HY-124177C14 Ceramide -
Similarity Score 0.91
HY-124177AC14 Ceramide (d18:1/14:0) -
Similarity Score 0.91
HY-179805C24:0 Ceramide (d18:2(4E,8Z)/24:0) -
Similarity Score 0.91
HY-166315C15-Ceramide -
Explore the MedChemAI to find more analogs
References
- [1]. Blachnio-Zabielska AU, et al. The Crucial Role of C18-Cer in Fat-Induced Skeletal Muscle Insulin Resistance. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2016;40(5):1207-1220.
- [2]. Wang K, et al. Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress. Cell death & disease. 2020 Jan 16;11(1):28.
- [3]. Wang K, et al. Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system. Cell death & disease. 2016 Mar 03;7(3):e2124.
