Hemitoxin
Hemitoxin, a scorpion-venom peptide, is a K+ channel blocker. Hemitoxin blocks rat Kv1.1, Kv1.2 and Kv1.3 channels expressed in Xenopus oocytes with IC50 values of 13 nM, 16 nM and 2 nM, respectively.
For research use only. We do not sell to patients.
- Formula: C159H259N49O49S8
- Molecular Weight:3897.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 3897.58
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Formula C159H259N49O49S8
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Sequence
Ile-Lys-Cys-Thr-Leu-Ser-Lys-Asp-Cys-Tyr-Ser-Pro-Cys-Lys-Lys-Glu-Thr-Gly-Cys-Pro-Arg-Ala-Lys-Cys-Ile-Asn-Arg-Asn-Cys-Lys-Cys-Tyr-Gly-Cys-Ser (Disulfide bridge:Cys3-Cys24;Cys9-Cys29;Cys13-Cys19;Cys31-Cys34)
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Sequence Shortening
IKCTLSKDCYSPCKKETGCPRAKCINRNCKCYGCS (Disulfide bridge:Cys3-Cys24;Cys9-Cys29;Cys13-Cys19;Cys31-Cys34)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)