PCSK9 ligand 1
PCSK9 ligand 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) ligand. PCSK9 ligand 1 does not affect PCSK9 function.
For research use only. We do not sell to patients.
- CAS No.: 2215931-60-3
- Formula: C34H34FN3O6S
- Molecular Weight:631.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Biphenyl acid PCSK9 ligand 1 (compound 9) binds to and thermally stabilizes PCSK9 in a complex environment such as Huh7 lysate[1].
PCSK9 ligand 1 (compound 9), with high affinity for recombinant PCSK9 and target engagement in cell lysate, could be used as a recruiting element to promote the selective degradation of PCSK9[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2215931-60-3
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Appearance Solid
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Molecular Weight 631.71
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Formula C34H34FN3O6S
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Color White to off-white
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SMILES
O=C(NC1=NC=CS1)C[C@@]2(C3=CC(OC4=CC(F)=C(C5=CC=C(C=C5)C(O)=O)C=C4)=C(OCC6CCCCO6)C=C3CCN2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)