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Cat. No.: HY-155809

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BET-IN-17

BET-IN-17 (compound 16) is a pan-inhibitor of BET with pIC₅₀s of 7.8 and 7.6 for BET BD1 and BET BD2, respectively.

For research use only. We do not sell to patients.

Formula: C₃₀H₃₆N₄O₂
Molecular Weight:484.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

BET-IN-17 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

BET-IN-17 (compound 16) is a pan-inhibitor of BET with pIC₅₀s of 7.8 and 7.6 for BET BD1 and BET BD2, respectively^[1].

IC₅₀ & Target

pIC50: 7.8 (BET BD1), 7.6 (BET BD2)^[1]

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Chemical Information

Molecular Weight 484.63
Formula C₃₀H₃₆N₄O₂
SMILES

CN1C=CC2=C([C@H](C1=O)C)C=CC(CN3CCN(CC3)CC4=CC=C5[C@H](C(N(C=CC5=C4)C)=O)C)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bamborough P, et al. Design and Characterization of 1, 3-Dihydro-2 H-benzo [d] azepin-2-ones as Rule-of-5 Compliant Bivalent BET Inhibitors[J]. ACS Medicinal Chemistry Letters, 2023.. . .

Calculators

Molarity Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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BET-IN-17

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Biological Activity

Description

IC50 & Target

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BET-IN-17 Related Classifications

HY-155809 Related Classifications

Bioz

Keywords

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