(−)-L-threo-PDMP hydrochloride

Cat. No.: HY-116392A: Ficha de datos Instrucciones de manejo
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(−)-L-threo-PDMP hydrochloride is the hydrochloride form of (−)-L-threo-PDMP. L-threo-PDMP is a glucosylceramide synthase (GCS) inhibitor. L-threo-PDMP stimulates the proliferation of cultured aortic smooth muscle cells, and that increases the level of LacCer in B16 melanoma cells.

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(−)-L-threo-PDMP hydrochloride Estructura química

No. CAS : 161491-04-9

Tamaño	Stock	Cantidad
1 mg	Obtener un presupuesto 2 - 3 weeks 4 - 5 weeks 5 - 6 weeks 1 - 2 weeks	Estimated Time of Arrival: December 31
5 mg	Obtener un presupuesto 2 - 3 weeks 4 - 5 weeks 5 - 6 weeks 1 - 2 weeks	Estimated Time of Arrival: December 31
10 mg	Obtener un presupuesto
50 mg	Obtener un presupuesto

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Based on 1 publication(s) in Google Scholar

Other Forms of (−)-L-threo-PDMP hydrochloride:

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Revisión del cliente

Descripciòn	(−)-L-threo-PDMP hydrochloride is the hydrochloride form of (−)-L-threo-PDMP. L-threo-PDMP is a glucosylceramide synthase (GCS) inhibitor. L-threo-PDMP stimulates the proliferation of cultured aortic smooth muscle cells, and that increases the level of LacCer in B16 melanoma cells^[1]^[2].
Peso molecular	427.02
Fòrmula	C₂₃H₃₉ClN₂O₃
No. CAS	161491-04-9
SMILES	CCCCCCCCCC(N[C@@H](CN1CCOCC1)[C@H](C2=CC=CC=C2)O)=O.Cl
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación	Ficha de datos (265 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Mitchell SA, et al. Glycosyltransferase Inhibitors: Synthesis of D-threo-PDMP, L-threo-PDMP, and Other Brain Glucosylceramide Synthase Inhibitors from D-or L-Serine. The Journal of Organic Chemistry. 1998, 63(24): 8837-8842. [2]. Chatterjee S, et al. Studies of the action of ceramide-like substances (D- and L-PDMP) on sphingolipid glycosyltransferases and purified lactosylceramide synthase. Glycoconj J. 1996 Jun;13(3):481-6. [Content Brief]