1. Anti-infection
    Metabolic Enzyme/Protease
  2. HIV Protease
  3. HIV-1 protease-IN-7

HIV-1 protease-IN-7 

Cat. No.: HY-151250
Handling Instructions

HIV-1 protease-IN-7 (compound 16) is an orally active HIV-1 protease inhibitor (IC50=3.52 nM, EC50=37 nM).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

HIV-1 protease-IN-7 Chemical Structure

HIV-1 protease-IN-7 Chemical Structure

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HIV-1 protease-IN-7 (compound 16) is an orally active HIV-1 protease inhibitor (IC50=3.52 nM, EC50=37 nM)[1].

IC50 & Target

HIV-1 protease[1].

In Vivo

HIV-1 protease-IN-7 (2.57 mg/kg; p.o.; single) exhibits good plasma total clearance and oral bioavailability[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (8-week-old)[1].
Dosage: 2.57 mg/kg (2 μM/kg)
Administration: Oral administration; single.
Result: 1.19 Pharmacokinetic Parameters of HIV-1 protease-IN-7 in male Sprague-Dawley rats[1].
metabolic stability rat/human (%) CLtot (mL/min/kg) Vdss (L/kg) t1/2 (h) F (%) serum fu(%)
PO (2.57 mg/kg) 63/23 8.2 1.9 3.9 3.3 0.1
Molecular Weight





Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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