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Salmonella typhimurium LT2 strains TA 100

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2610

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105

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133

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101

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2

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404

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37

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1124

Click Chemistry

84

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3

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130320

    Glucopyranosyl lipid A

    Toll-like Receptor (TLR) Inflammation/Immunology Cancer
    Monophosphoryl lipid A (Glucopyranosyl lipid A) is a toll-like receptor 4 agonist. Monophosphoryl lipid A is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A can be used for the research of immunization and vaccine .
    Monophosphoryl lipid A
  • HY-128525

    Bacterial Reactive Oxygen Species (ROS) Infection Inflammation/Immunology
    Enterobactin is a siderophore produced by Gram-negative bacteria and has an extremely high affinity for iron. During the process of Salmonella typhimurium infecting macrophages, Enterobactin can not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages. In addition, Enterobactin is also involved in the oxidative stress response of Escherichia coli. Enterobactin can be hydrolyzed by Fes in the cell and exert antioxidant effects by scavenging free radicals [2].
    Enterobactin
  • HY-17390A
    Loxapine succinate
    1 Publications Verification

    5-HT Receptor Dopamine Receptor Infection Neurological Disease
    Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages .
    Loxapine succinate
  • HY-B0455

    SC47111A hydrochloride; NY-198 hydrochloride

    Antibiotic Bacterial Topoisomerase Reactive Oxygen Species (ROS) Apoptosis Infection Endocrinology Cancer
    Lomefloxacin hydrochloride (NY-198 hydrochloride) is an orally active difluoroquinolone antibiotic. Lomefloxacin hydrochloride prevents DNA supercoiling and replication by inhibiting bacterial topoisomerase II. Lomefloxacin hydrochloride induces ROS production and Apoptosis. Lomefloxacin hydrochloride has broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria. Lomefloxacin hydrochloride has anticancer effects against melanoma. Lomefloxacin hydrochloride can be used in the study of systemic bacterial infections (such as Salmonella typhimurium infections), skin and melanoma [2] .
    Lomefloxacin hydrochloride
  • HY-W088066

    Bacterial Infection
    Trisodium phosphate dodecahydrate is an Antibacterial agent. Trisodium phosphate dodecahydrate reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate is used in poultry processing [2].
    Trisodium phosphate (dodecahydrate)
  • HY-W020246

    TMTM

    Squalene Monooxygenase Bacterial Infection Inflammation/Immunology
    Tetramethylthiuram monosulfide (TMTM) is an orally active microsomal monooxygenases inhibitor. Tetramethylthiuram monosulfide is used as an accelerator and activator in the processing of natural rubber and butyl rubber. Tetramethylthiuram monosulfide reduces palmitic acid incorporation into microsomal phospholipids, disrupts microsomal membrane integrity, and impairs electron transport during oxygenation. Tetramethylthiuram monosulfide can be used for the research of fungal infection, bacterial infection and allergic contact dermatitis [2].
    Tetramethylthiuram monosulfide
  • HY-W540978

    Biochemical Assay Reagents Others
    3-Azido-7-hydroxycoumarin is a click chemistry reagent containing an azido group. Under Cu (II) catalysis, it undergoes azide-alkyne cycloaddition (CuAAC) click reaction with 3-butyn-1-ol and emits a fluorescent signal .
    3-Azido-7-hydroxycoumarin
  • HY-D1056C5

    LPS, from Salmonella enterica (Serotype minnesoTA Re 595 (Re muTAnt))

    Toll-like Receptor (TLR) Bacterial Inflammation/Immunology
    Lipopolysaccharides (LPS), from S. enterica (Salmonella enterica) serotype minnesota Re 595 (Re mutant) is prepared from Salmonella enterica strain Re 595 (Re mutant). The structure in the LPS of strain Re 595 was shown to induce secretion and aggregation in human platelets .
    It is recommended to prepare a solution with concentration 2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
    Lipopolysaccharides, from S. enterica serotype minnesota Re 595 (Re mutant)
  • HY-126569

    Antibiotic Bacterial Infection
    Efrotomycin is an orally active antibiotic. Efrotomycin can be isolated from the Streptomyces Lactamdurans. Efrotomycin has insignificant effect on Salmonella typhimurium quantity, duration, shedding rate, and antimicrobial susceptibility in infected pigs [2].
    Efrotomycin
  • HY-NP134

    Toll-like Receptor (TLR) MyD88 NF-κB Interleukin Related IFNAR Inflammation/Immunology Cancer
    Flagellin from S. typhimurium is a potent TLR5 agonist. Flagellin from S. typhimurium activates immune cells and inhibits the activity of melanoma cells. Flagellin from S. typhimurium activates the NF-κB pathway dependent on the TLR5/MyD88/TRAF6 signaling axis in cells. Flagellin from S. typhimurium induces a proinflammatory response in the primary chicken hepatocyte-nonparenchymal cell co-culture system by promoting IL-8 production, inhibiting IL-10 production, and increasing the IFN-γ/IL-10 ratio. Flagellin from S. typhimurium can be used for research on melanoma and inflammatory diseases [2].
    Flagellin from S. typhimurium
  • HY-P3302

    Bacterial Infection
    Sialylglycopeptide is an orally active glycopeptide found in egg yolk. Sialylglycopeptide inhibits the binding of Salmonella enteritidis and Escherichia coli to intestinal cells, and protects mice from Salmonella infection. Sialylglycopeptide can be used in the research of Salmonella infection .
    Sialylglycopeptide
  • HY-B0455A

    SC47111A; NY-198

    Bacterial Antibiotic Topoisomerase Reactive Oxygen Species (ROS) Apoptosis Infection
    Lomefloxacin (SC47111A) is an orally active difluoroquinolone antibiotic. Lomefloxacin prevents DNA supercoiling and replication by inhibiting bacterial topoisomerase II. Lomefloxacin induces ROS production and Apoptosis. Lomefloxacin has broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria. Lomefloxacin has anticancer effects against melanoma. Lomefloxacin can be used in the study of systemic bacterial infections (such as Salmonella typhimurium infections), skin and melanoma [2] .
    Lomefloxacin
  • HY-119543

    Amino Acid Derivatives Others
    O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .
    O-Succinyl-L-homoserine
  • HY-D1056B4

    LPS, from bacterial (Salmonella typhosa)

    Toll-like Receptor (TLR) Inflammation/Immunology
    Lipopolysaccharides, from Salmonella typhosa are lipopolysaccharide endotoxins and TLR-4 activators derived from Salmonella typhosa, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from Salmonella typhosa exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from Salmonella typhosa can serve as vaccine adjuvants and demonstrate adjuvant activity targeting B cells in immune responses in vivo .
    It is recommended to prepare a solution with concentration 2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
    Lipopolysaccharides, from Salmonella typhosa
  • HY-W275553

    DNA Alkylator/Crosslinker Infection
    4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of Aflatoxin B1 (HY-N6615) and MNNG (HY-128612) in Salmonella typhimurium TA100 [2].
    4-Decanol
  • HY-D1056C3

    LPS, from Salmonella enterica (Serotype typhimurium)

    Toll-like Receptor (TLR) Inflammation/Immunology
    Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype typhimurium are lipopolysaccharide endotoxins and TLR4 activators derived from serotype typhimurium of Salmonella enterica, and are classified as S-type LPS. Lipopolysaccharides, from S. enterica exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from S. enterica serotype typhimurium can modulate the fate of bacteria in dendritic cells (DC), determining the uptake, degradation, and activation of immune functions by DC cells against the bacteria [2] .
    It is recommended to prepare a solution with concentration 2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
    Lipopolysaccharides, from S. enterica serotype typhimurium
  • HY-W008030

    Bacterial Infection
    3-Aminobiphenyl is a chemical isomer of 4-ABP. 3-Aminobiphenyl can inhibit the growth of human intestinal bacteria Bifidobacterium infantis ATCC 15697, B. bifidium ATCC 11863, Clostridium perfringens ATCC 13124, Escherichia coli ATCC 25922, E. coli ATCC 35218, Enterobacter cloacae ATCC 13047 and Salmonella typhimurium TA98, TA100, YG1041. 3-Aminobiphenyl can be used as a biomarker of exposure to aromatic amines from cigarette smoke [2].
    3-Aminobiphenyl
  • HY-P2988E

    Endogenous Metabolite Metabolic Disease
    α2-3 Neuraminidase, Salmonella typhimurium LT2 is a glycoside hydrolase enzyme that cleave the glycosidic linkages of neuraminic acids.
    α2-3 Neuraminidase, Salmonella typhimurium LT2
  • HY-W001189

    Bacterial Infection
    1,3-Dithiane is a protected formaldehyde anion equivalent and a sulfur-containing Maillard reaction product. 1,3-Dithiane is found in cooked beef extracts. 1,3-Dithiane is a potent mutagenic agent against S. typhimurium TA98 and TA100. 1,3-Dithiane can be used as a useful marker synthon [2].
    1,3-Dithiane
  • HY-N10479

    DNA/RNA Synthesis Drug Intermediate Endogenous Metabolite Bacterial Infection
    Chorismic acid is a precursor for the biosynthesis of aromatic amino acids and vitamins, as well as a key metabolite in tRNA modification. Chorismic acid is a critical metabolite for the synthesis of cmo 5U. Deficiency of Chorismic acid inhibits the formation of cmo 5U and mcmo 5U. Chorismic acid can be used in studies of S. typhimurium and E. coli infections .\n


    Chorismic acid
  • HY-D1056C1

    LPS, from Salmonella enterica (Serotype enteritidis)

    Toll-like Receptor (TLR) Inflammation/Immunology
    Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype enteritidis are lipopolysaccharide endotoxins and TLR-4 activators derived from the enteritidis serotype of S. enterica, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from S. enterica serotype enteritidis exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from S. enterica serotype enteritidis can induce systemic inflammatory responses, increasing levels of TNF-α, IFN-γ, IL-6, IL-10, and nitrate in plasma [2].
    It is recommended to prepare a solution with concentration 2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
    Lipopolysaccharides, from S. enterica serotype enteritidis
  • HY-P990289

    Transmembrane Glycoprotein Infection
    Anti-Mouse CD172a Antibody (P84) is a rat-derived anti-mouse CD172a IgG1 κ type antibody inhibitor. Anti-Mouse CD172a Antibody (P84) blocks CD47-SIRPα interaction and thereby augments cell phagocytosis. Anti-Mouse CD172a Antibody (P84) can be used for the researches of infection and immunology, such as salmonella typhimurium infection [2] .
    Anti-Mouse CD172a Antibody (P84)
  • HY-B1852

    Bacterial Fungal Infection
    Sulfometuron-methyl is a herbicide and also a powerful inhibitor of the enzyme acetolactate synthase (ALS). It exhibits antibacterial and antifungal activities, capable of inhibiting the activity of Salmonella. typhimurium ALS II and Escherichia. coli ALS III .
    Sulfometuron-methyl
  • HY-W854341

    Antibiotic Bacterial Infection
    Chitotriose is a chitooligosaccharide that can be isolated from crab shell chitosan. Chitotriose has antibacterial effect against salmonella .
    Chitotriose
  • HY-P5016A

    Antibiotic Fungal Bacterial Infection Cancer
    CRAMP-18 (mouse) acetate is an antibiotic peptide without hemolytic activity. CRAMP-18 (mouse) acetate has good inhibitory activity against Gram-negative bacteria, such as S. typhimurium and P. aeruginosa. CRAMP-18 (mouse) acetate has the potential to study antifungal, antibacterial and antitumor [2].
    CRAMP-18 (mouse) acetate
  • HY-133735A
    GRP-60367 hydrochloride
    1 Publications Verification

    RABV Infection
    GRP-60367 hydrochloride is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains. GRP-60367 hydrochloride specifically targets the RABV G protein .
    GRP-60367 hydrochloride
  • HY-154171

    Nucleoside Antimetabolite/Analog Others
    Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one (Compound dP) exhibits mutagenicity for Escherichia coli and Salmonella typhimurium, that induces the conversion between GC and AT through replication error. eoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one is stable in Escherichia coli, and can be detected at wavelength >300 nM .
    Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one
  • HY-W150695

    N-(Naphthalen-1-yl)aceTAmide

    Bacterial Infection
    1-Acetamidonaphthalene (N-(Naphthalen-1-yl)acetamide) is a degradation product of Digitoxigenin (HY-B2151). 1-Acetamidonaphthalene is weakly mutagenic to Salmonella typhimurium TA98 with metabolic activation. 1-Acetamidonaphthalene can be used for the research of bacterial infection [2].
    1-Acetamidonaphthalene
  • HY-N5054

    TNF Receptor Inflammation/Immunology
    (R)-5,7-Dimethoxyflavanone shows potent antimutagenic activity against MeIQ mutagenesis in Ames test using the S. typhimurium TA100 and TA98 strains . And (R)-5,7-Dimethoxyflavanone significantly and dose-dependently inhibits the inflammatory mediato .
    (R)-5,7-Dimethoxyflavanone
  • HY-157368

    Biochemical Assay Reagents Infection
    Bismuth Sulfite Agar is a selective solid medium that can be used for the isolation, determination and culture of Salmonella .
    Bismuth Sulfite Agar
  • HY-N3549

    Bacterial Infection
    Catalpin is an iridoid that can be isoalted from Catalpae Fructus.Catalpin shows mutagenic activity towards Salmonella typhimurium strain TA100 .
    Catalpin
  • HY-17390AR

    Reference Standards 5-HT Receptor Dopamine Receptor Infection Neurological Disease
    Loxapine (succinate) (Standard) is the analytical standard of Loxapine (succinate). This product is intended for research and analytical applications. Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages .
    Loxapine succinate (Standard)
  • HY-B1568A

    Ambodryl hydrochloride

    Histamine Receptor Bacterial Infection Inflammation/Immunology
    Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research [2] .
    Bromodiphenhydramine hydrochloride
  • HY-W088066A

    Bacterial Infection
    Trisodium phosphate dodecahydrate, 98% is an Antibacterial agent. Trisodium phosphate dodecahydrate, 98% reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate, 98% modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate, 98% is used in poultry processing [2].
    Trisodium phosphate (dodecahydrate), 98%
  • HY-133735
    GRP-60367
    1 Publications Verification

    RABV Infection
    GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains .
    GRP-60367
  • HY-157380

    SS Agar

    Biochemical Assay Reagents Others
    Salmonella-Shigella Agar (SS Agar) is a solid medium that can be used for the isolation, detection and culture of Salmonella and Shigella.
    Salmonella-Shigella Agar
  • HY-146394

    HBV DNA/RNA Synthesis Infection
    HBV-IN-22 (Compound LC5f) is an inhibitor of HBV DNA replication with IC50 values of 0.71 μM and 0.84 μM against wild-type and agent resistant HBV strains, respectively .
    HBV-IN-22
  • HY-141467S

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Propionyl CoA-d5 is the deuterium labeled Propionyl CoA (HY-141467). Propionyl CoA serves as a common intermediate in the catabolic pathways of 1,2-propanediol and propionate in Salmonella enterica serovar Typhimurium LT2, and also functions as a precursor for 2-methylcitrate. Propionyl CoA is utilized as a substrate for the 2-methylcitrate synthase (PrpC) enzyme to synthesize 2-methylcitrate .
    Propionyl CoA-d5
  • HY-126461

    Bacterial Fungal Infection
    Salazinic acid has antibacterial activity against bacteria and fungi. Salazinic acid does not show antibacterial activity against Listeria monocytogenes, Pseudomonas aeruginosa, Yersinia enterocolitica, and Enterococcus faecalis, but it does have antibacterial activity against Pseudomonas aeruginosa and Salmonella typhimurium .
    Salazinic acid
  • HY-163292

    Bacterial Parasite Infection
    Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102) .
    Antibacterial agent 180
  • HY-N17457

    Bacterial Infection
    N-Demethyl-N-formyldehydronuciferine is a dehydroaporphine alkaloid. N-Demethyl-N-formyldehydronuciferine induces mutations in Salmonella typhimurium TA98 and TA100 .
    N-Demethyl-N-formyldehydronuciferine
  • HY-121345

    Drug Metabolite Neurological Disease Cancer
    Homobaldrinal is a decomposition product of Valepotriate (HY-N0718). Homobaldrinal exhibits genotoxic activity in the Salmonella/microsome test .
    Homobaldrinal
  • HY-W250061

    Others Cancer
    (-)-(1S,3S)-MTCA can be isolated from Japanese soy sauce. (-)-(1S,3S)-MTCA induces revertants of Salmonella typhimurium TA100, after treatment with nitrite .
    (-)-(1S,3S)-MTCA
  • HY-157369

    Biochemical Assay Reagents Others
    Salmonella Arizona Agar is a special medium for Salmonella Arizona. The composition of 1 litre medium is 88.5 g Salmonella Arizona Agar .
    Salmonella Arizona Agar
  • HY-24366

    Bacterial DNA/RNA Synthesis Infection
    Quindoxin is an antibacterial and growth promoter, commonly used in the livestock industry. Quindoxin exhibits clear dose-dependent mutagenic activity against Salmonella typhimurium TA98 and TA100 strains. Quindoxin can cause DNA damage and has potential genotoxicity and carcinogenic risks .
    Quindoxin
  • HY-B1568

    Ambodryl

    Histamine Receptor Bacterial Infection Inflammation/Immunology
    Bromodiphenhydramine (Ambodryl) is a potent antihistamine with antimicrobial property. Bromodiphenhydramine inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine can be used for cutaneous allergies research [2] .
    Bromodiphenhydramine
  • HY-139982

    Bacterial Infection
    OX11 is a selective inhibitor of S. pneumoniae, P. aeruginosa, and E. coli bacterial strains .
    OX11
  • HY-186055

    Parasite Infection
    Antimalarial agent 58 is a diaminoquinoline methanol compound with weak in vitro activity against Plasmodium falciparum strain D6, and no activity against Plasmodium falciparum strains W2, C235 and C2A .
    Antimalarial agent 58
  • HY-170219

    Parasite Epigenetic Reader Domain Infection
    RMM23 is an inhibitor targeting PfBDP1 with a Kd value of 1.24 μM. RMM23 against the wild-type strains 3D7 and NF54, and the multidrug-resistant K1 strain in vitro blood stage, with EC50 values of 18 μM, 14 μM, 20 μM, respectively .
    RMM23
  • HY-158425

    Bacterial Infection
    Antimicrobial agent-31 (compound 4a) is a potent antimicrobial agent. Antimicrobial agent-31 inhibits Salmonella enterica serovar Typhimurium and E.coli with MIC values of 19.24, 11.31 µg/mL, respectively .
    Antimicrobial agent-31

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