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  2. PROTAC Linker
  3. Azido-PEG1-CH2COO-Cl

Azido-PEG1-CH2COO-Cl 

Cat. No.: HY-130984
Handling Instructions

Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131).

For research use only. We do not sell to patients.

Azido-PEG1-CH2COO-Cl Chemical Structure

Azido-PEG1-CH2COO-Cl Chemical Structure

CAS No. : 79598-49-5

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Description

Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131)[1].

IC50 & Target[1]

Alkyl/ether

 

In Vitro

PROTAC BRD4 Degrader-1 is an efficacious BRD4 degrader with an IC50 of 41.8 nM against BRD4 BD1. PROTAC BRD4 Degrader-1 can effectively degrade BRD4 protein and suppress c-Myc expression[1].

Molecular Weight

163.56

Formula

C₄H₆ClN₃O₂

CAS No.

79598-49-5

SMILES

O=C(Cl)COCCN=[N+]=[N-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Azido-PEG1-CH2COO-ClPROTAC LinkerInhibitorinhibitorinhibit

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Azido-PEG1-CH2COO-Cl
Cat. No.:
HY-130984
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