Hepcidin-20 (human)
Hepcidin-20 (human) is a histidine-containing, cysteine-rich, β-sheet structured peptide. Hepcidin-20 (human) shows antifungal activity. Hepcidin-20 (human) inhibits biofilm formation and bacterial cell metabolism of polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains.
For research use only. We do not sell to patients.
- CAS No.: 342790-23-2
- Formula: C85H135N27O23S9
- Molecular Weight:2191.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 342790-23-2
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Molecular Weight 2191.73
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Formula C85H135N27O23S9
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Sequence
Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr (Disulfide bridge: Cys2-Cys8,Cys5-Cys18,Cys6-Cys17,Cys9-Cys14)
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Sequence Shortening
ICIFCCGCCHRSKCGMCCKT (Disulfide bridge: Cys2-Cys8,Cys5-Cys18,Cys6-Cys17,Cys9-Cys14)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Maisetta G, et al. pH-dependent disruption of Escherichia coli ATCC 25922 and model membranes by the human antimicrobial peptides hepcidin 20 and 25. FEBS J. 2013 Jun;280(12):2842-54. [Content Brief]
[2]. Del Gaudio G, et al. Antifungal Activity of the Noncytotoxic Human Peptide Hepcidin 20 against Fluconazole-Resistant Candida glabrata in Human Vaginal Fluid. Antimicrob Agents Chemother. 2013 Sep;57(9):4314-4321. [Content Brief]
[3]. Brancatisano FL, et al. Inhibitory effect of the human liver-derived antimicrobial peptide hepcidin 20 on biofilms of polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains of Staphylococcus epidermidis. Biofouling. 2014;30(4):435-46. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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