1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. 8-Azido-ATP

8-Azido-ATP (Synonyms: 8-Azidoadenosine 5'-triphosphate; 8-N3-ATP)

Cat. No.: HY-134320
Handling Instructions

8-Azido-ATP, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase.

For research use only. We do not sell to patients.

8-Azido-ATP Chemical Structure

8-Azido-ATP Chemical Structure

CAS No. : 53696-59-6

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8-Azido-ATP, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase[1].

In Vitro

8-Azido-ATP can be used to identify the viral RNA polymerase on the basis of the ability of the analog to inhibit transcription activity associated with rotavirus particles on exposure to UV light[1].
8-Azido-ATP (azido-ATP) decreases viral transcription in a dose-dependent manner[1].
8-Azido-ATP blocks Kir6.2ΔC26 currents rather less potently than ATP, half-maximal inhibition (Ki) occurring at 2.8 ± 0.4 mM (n = 6) compared with 172 ± 7 mM for ATP (n = 6). The Hill coefficients were 0.9 ± 0.2 for 8-azido-ATP and 1.3 ± 0.1 for ATP[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





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8-Azido-ATP8-Azidoadenosine 5'-triphosphate 8-N3-ATPPotassium ChannelKcsAphotoreactablenucleotideanalogKir6.2ATProtavirusInhibitorinhibitorinhibit

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