1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. 8-Azido-ATP

8-Azido-ATP (Synonyms: 8-Azidoadenosine 5'-triphosphate; 8-N3-ATP)

Cat. No.: HY-134320
Handling Instructions

8-Azido-ATP, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase.

For research use only. We do not sell to patients.

8-Azido-ATP Chemical Structure

8-Azido-ATP Chemical Structure

CAS No. : 53696-59-6

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

8-Azido-ATP, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase[1].

In Vitro

8-Azido-ATP can be used to identify the viral RNA polymerase on the basis of the ability of the analog to inhibit transcription activity associated with rotavirus particles on exposure to UV light[1].
8-Azido-ATP (azido-ATP) decreases viral transcription in a dose-dependent manner[1].
8-Azido-ATP blocks Kir6.2ΔC26 currents rather less potently than ATP, half-maximal inhibition (Ki) occurring at 2.8 ± 0.4 mM (n = 6) compared with 172 ± 7 mM for ATP (n = 6). The Hill coefficients were 0.9 ± 0.2 for 8-azido-ATP and 1.3 ± 0.1 for ATP[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

548.19

Formula

C₁₀H₁₅N₈O₁₃P₃

CAS No.
SMILES

O[[email protected]@H]([[email protected]]([[email protected]](N1C(N=[N+]=[N-])=NC2=C(N=CN=C21)N)O3)O)[[email protected]]3COP(O)(OP(OP(O)(O)=O)(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

8-Azido-ATP8-Azidoadenosine 5'-triphosphate 8-N3-ATPPotassium ChannelKcsAphotoreactablenucleotideanalogKir6.2ATProtavirusInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
8-Azido-ATP
Cat. No.:
HY-134320
Quantity:
MCE Japan Authorized Agent: