Tuberculosis inhibitor 3
Based on 1 Customer Validation
Tuberculosis inhibitor 3 (compound 2i) displays potent anti-TB activity (MIC < 0.016 μg/mL) against agent-sensitive/resistant MTB strains. Tuberculosis inhibitor 3 (compound 2i) shows acceptable PK profiles with oral bioavailability.
For research use only. We do not sell to patients.
- Purity: 98.62%
- CAS No.: 2219325-28-5
- Formula: C21H22F6N4O3S
- Molecular Weight:524.48
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Anti-Infection Compound Library
HY-L002
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Immunology/Inflammation Compound Library
HY-L007
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Antibacterial Compound Library
HY-L049
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Anti-tuberculosis Compound Library
HY-L142
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Anti-Drug-Resistant Compound Library
HY-L169
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MCE Bioactive Compound Library
HY-L001V
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Tuberculosis inhibitor 3 (compound 2i, 50 mg/kg) shows acceptable PK properties with the AUC of 2489 h ng/mL) is. The Tmax of Tuberculosis inhibitor 3 is 0.25 h[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2219325-28-5
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Appearance Solid
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Molecular Weight 524.48
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Formula C21H22F6N4O3S
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Color White to yellow
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SMILES
O=C1C2=CC(C(F)(F)F)=CC([N+]([O-])=O)=C2SC(N3CCC(CN4CCC(C(F)(F)F)CC4)CC3)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 27.5 mg/mL (52.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9067 mL | 9.5333 mL | 19.0665 mL | 47.6663 mL |
| 5 mM | 0.3813 mL | 1.9067 mL | 3.8133 mL | 9.5333 mL | |
| 10 mM | 0.1907 mL | 0.9533 mL | 1.9067 mL | 4.7666 mL | |
| 15 mM | 0.1271 mL | 0.6356 mL | 1.2711 mL | 3.1778 mL | |
| 20 mM | 0.0953 mL | 0.4767 mL | 0.9533 mL | 2.3833 mL | |
| 25 mM | 0.0763 mL | 0.3813 mL | 0.7627 mL | 1.9067 mL | |
| 30 mM | 0.0636 mL | 0.3178 mL | 0.6356 mL | 1.5889 mL | |
| 40 mM | 0.0477 mL | 0.2383 mL | 0.4767 mL | 1.1917 mL | |
| 50 mM | 0.0381 mL | 0.1907 mL | 0.3813 mL | 0.9533 mL |
Tuberculosis inhibitor 3 Related Classifications
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