(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin
(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Formula: C57H81N11O19
- Molecular Weight:1144.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1144.34
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Formula C57H81N11O19
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SMILES
CN(C1=CC2=C(C(C3=CC=C(C(NCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCC(NCCOCCOCCOCCNC(CCCCC[C@@H]4[C@H](C)NC(N4)=O)=O)=O)=O)=O)C=C3C([O-])=O)=C5C=C/C(C=C5O2)=[N+](C)/C)C=C1)C.CN(C6=CC7=C(C(C8=CC(C(NCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCC(NCCOCCOCCOCCNC(CCCCC[C@@H]9[C@H](C)NC(N9)=O)=O)=O)=O)=O)=CC=C8C([O-])=O)=C%10C=C/C(C=C%10O7)=[N+](C)/C)C=C6)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin Related Classifications
HY-140948 Related Classifications
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