1. PROTAC
  2. PROTAC Linker
  3. (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin

(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin 

Cat. No.: HY-140948
Handling Instructions

(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin Chemical Structure

(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin Chemical Structure

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Description

(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1144.30

Formula

C₅₇H₈₁N₁₁O₁₄

SMILES

C/[N+](C)=C1=CC2=C(C(C3=CC=C(C(NCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCC(NCCOCCOCCOCCNC(CCCCC[[email protected]@H]4[[email protected]](C)NC(N4)=O)=O)=O)=O)=O)C=C3C([O-])=O)=C5C=CC(N(C)C)C=C5O2)C=C\1.C/[N+](C)=C6=CC7=C(C(C8=CC(C(NCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCC(NCCOCCOCCOCCNC(CCCCC[[email protected]@H]9[[email protected]](C)NC(N9)=O)=O)=O)=O)=O)=CC=C8C([O-])=O)=C%10C=CC(N(C)C)C=C%10O7)C=C\6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

(5,6)TAMRA-PEG3-Azide-PEG3-DesthiobiotinPROTAC LinkerInhibitorinhibitorinhibit

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Product Name:
(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin
Cat. No.:
HY-140948
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