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Cat. No.: HY-149456

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Xanthoangelol F

Xanthoangelol F is a prenylated (geranylated) chalcone and Antibacterial agent. Xanthoangelol F can be isolated from Angelica keiskei. Xanthoangelol F inhibits the growth of Gram-positive bacteria Bacillus subtilis, Staphylococcus epidermidis, and Micrococcus luteus, with an MIC of 64 μg/mL.

For research use only. We do not sell to patients.

CAS No.: 265652-71-9
Formula: C₂₆H₃₀O₄
Molecular Weight:406.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Xanthoangelol F Chemical Structure

CAS No.: 265652-71-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

In Vitro

Xanthoangelol F (20 μM) does not inhibit the SaeRS two-component system in Staphylococcus aureus USA300-Phlam-GFP strain^[1].
Xanthoangelol F (1-256 μg/mL; 48 h) inhibits the growth of Gram-positive Bacillus subtilis, Staphylococcus epidermidis, and Micrococcus luteus with an MIC of 64 μg/mL, and shows no activity against tested Gram-negative bacteria^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 265652-71-9
Molecular Weight 406.52
Formula C₂₆H₃₀O₄
SMILES

C(/C=C(/CCC=C(C)C)\C)C1=C(OC)C=CC(C(/C=C/C2=CC=C(O)C=C2)=O)=C1O
Structure Classification
- Flavonoids
- Chalcones
- Phenols
- Polyphenols
Initial Source
- Plants
- Umbelliferae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mizar P, et al. Total Synthesis of Xanthoangelol B and Its Various Fragments: Toward Inhibition of Virulence Factor Production of Staphylococcus aureus. J Med Chem. 2018;61(23):10473-10487. [Content Brief]

[2]. Sugamoto K, et al. Synthesis and antibacterial activity of chalcones bearing prenyl or geranyl groups from Angelica keiskei[J]. Tetrahedron, 2011, 67(29): 5346-5359.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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