4-(Azidomethyl)benzoic acid

Cat. No.: HY-151854 Purity: 99.95%: Data Sheet
COA

SDS
Handling Instructions
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4-(Azidomethyl)benzoic acid is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

4-(Azidomethyl)benzoic acid Chemical Structure

CAS No. : 79584-03-5

Size	Stock	Quantity
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Purity & Documentation
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Description

4-(Azidomethyl)benzoic acid is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity^[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Molecular Weight

177.16

Formula

C₈H₇N₃O₂

CAS No.

79584-03-5

Appearance

Solid

Color

White to off-white

SMILES

[N-]=[N+]=NCC1=CC=C(C(O)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (564.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.6446 mL	28.2231 mL	56.4461 mL
5 mM	1.1289 mL	5.6446 mL	11.2892 mL
10 mM	0.5645 mL	2.8223 mL	5.6446 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.95%

Select Batch:

Data Sheet (268 KB) SDS (779 KB)

COA (244 KB) HNMR (156 KB) RP-HPLC (226 KB) MS (77 KB)

Handling Instructions (2659 KB)

References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.6446 mL	28.2231 mL	56.4461 mL	141.1154 mL
	5 mM	1.1289 mL	5.6446 mL	11.2892 mL	28.2231 mL
	10 mM	0.5645 mL	2.8223 mL	5.6446 mL	14.1115 mL
	15 mM	0.3763 mL	1.8815 mL	3.7631 mL	9.4077 mL
	20 mM	0.2822 mL	1.4112 mL	2.8223 mL	7.0558 mL
	25 mM	0.2258 mL	1.1289 mL	2.2578 mL	5.6446 mL
	30 mM	0.1882 mL	0.9408 mL	1.8815 mL	4.7038 mL
	40 mM	0.1411 mL	0.7056 mL	1.4112 mL	3.5279 mL
	50 mM	0.1129 mL	0.5645 mL	1.1289 mL	2.8223 mL
	60 mM	0.0941 mL	0.4704 mL	0.9408 mL	2.3519 mL
	80 mM	0.0706 mL	0.3528 mL	0.7056 mL	1.7639 mL
	100 mM	0.0564 mL	0.2822 mL	0.5645 mL	1.4112 mL