3-Phenylphenol
Based on 1 Customer Validation
3-Phenylphenol is a secondary metabolite. 3-Phenylphenol can induce the hbp gene cluster in Pseudomonas sp. strain P1B16. 3-Phenylphenol can bind to the Sge1 transcription factor of Fusarium oxysporum f. sp. cubense and disrupt the function of virulence regulators. 3-Phenylphenol can be used in studies related to banana fusarium wilt.
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- Purity: 99.86%
- CAS No.: 580-51-8
- 화학식: C12H10O
- 분자량:170.21
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보관:
RT, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
25 μg/mL
Compound: 7
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Cytotoxicity against HEK293 cells assessed as reduction in cell growth after 3 days by MTT assay
Cytotoxicity against HEK293 cells assessed as reduction in cell growth after 3 days by MTT assay
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[PMID: 27259399] |
| HT-29 | IC50 |
28 μg/mL
Compound: 7
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Cytotoxicity against human HT-29 cells assessed as reduction in cell growth after 3 days by MTT assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth after 3 days by MTT assay
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[PMID: 27259399] |
| MCF7 | IC50 |
27.4 μg/mL
Compound: 7
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Cytotoxicity against human MCF7 cells assessed as reduction in cell growth after 3 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth after 3 days by MTT assay
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[PMID: 27259399] |
3-Phenylphenol (0.1-100 mM; 72 h) induces the hbp operon in the Pseudomonas sp. P1B16/egfp biosensor strain[1].
3-Phenylphenol exhibits strong binding affinity to the Sge1 protein of Fusarium oxysporum f. sp. cubense, with a binding energy of -6.7 kcal/mol[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 580-51-8
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Appearance Solid
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분자량 170.21
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화학식 C12H10O
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Color Off-white to light yellow
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SMILES
OC1=CC=CC(=C1)C=2C=CC=CC2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
RT, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
순도&문서
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Suman J, et al. Transformation of hydroxylated polychlorinated biphenyls by bacterial 2-hydroxybiphenyl 3-monooxygenase. Chemosphere. 2024;349:140909. [Content Brief]
[2]. Sonkar P, et al. In silico profiling, docking analysis, and protein interactions of secondary metabolites in Musa spp. Against the SGE1 protein of Fusarium oxysporum f. sp. cubense. Comput Biol Chem. 2024;113:108230. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3-Phenylphenol Related Classifications
HY-W016983 Related Classifications
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