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Cat. No.: HY-N9930

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Effusanin B

Effusanin B (Compound 3) is a diterpenoid can be isolated from Rabdosia effusa (Maxim.) Hara. Effusanin B (Compound 3) has antifungal activity.

For research use only. We do not sell to patients.

CAS No.: 76470-16-1
Formula: C₂₂H₃₀O₆
Molecular Weight:390.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Effusanin B Chemical Structure

CAS No.: 76470-16-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Effusanin B (Compound 3) is a diterpenoid can be isolated from Rabdosia effusa (Maxim.) Hara. Effusanin B (Compound 3) has antifungal activity^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	3.5 μM Compound: 15	Cytotoxicity against human A549 cells after 48 hrs by MTT method Cytotoxicity against human A549 cells after 48 hrs by MTT method	[PMID: 21534539]
Bel-7402	IC₅₀	7.3 μM Compound: 18	Cytotoxicity against human Bel7402 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human Bel7402 cells after 72 hrs by sulforhodamine B assay	[PMID: 20949916]
HL-60	IC₅₀	0.7 μM Compound: 15	Cytotoxicity against human HL60 cells after 48 hrs by MTT method Cytotoxicity against human HL60 cells after 48 hrs by MTT method	[PMID: 21534539]
HT-29	IC₅₀	4.1 μM Compound: 18	Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay	[PMID: 20949916]
MCF7	IC₅₀	0.7 μM Compound: 15	Cytotoxicity against human MCF7 cells after 48 hrs by MTT method Cytotoxicity against human MCF7 cells after 48 hrs by MTT method	[PMID: 21534539]
SK-OV-3	IC₅₀	2.1 μM Compound: 18	Cytotoxicity against human SKOV3 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human SKOV3 cells after 72 hrs by sulforhodamine B assay	[PMID: 20949916]
SMMC-7721	IC₅₀	1 μM Compound: 15	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT method Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT method	[PMID: 21534539]
SW480	IC₅₀	0.8 μM Compound: 15	Cytotoxicity against human SW480 cells after 48 hrs by MTT method Cytotoxicity against human SW480 cells after 48 hrs by MTT method	[PMID: 21534539]

In Vitro

Effusanin B (Compound 3) exhibits significant cytotoxic activity against DNA repair-deficient (RAD 52Y, mutant) yeast strains^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 76470-16-1
Molecular Weight 390.47
Formula C₂₂H₃₀O₆
SMILES

CC(O[C@@H]1[C@@]23[C@@]4([H])[C@]5(C[C@@](C(C5=O)=C)([H])CC4)[C@@]([C@H]([C@]2([H])C(C)(CC1)C)O)(OC3)O)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Abbaskhan A, et al. A new diepoxy-ent-kauranoid, rugosinin, from Isodon rugosus. Planta Med. 2003 Jan;69(1):94-6. [Content Brief]

[2]. Fujita T, et al. Structures of effusanins, antibacterial diterpenoids from Rabdosia effusa[J]. Chemistry Letters, 1980, 9(12): 1635-1638.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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