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Cat. No.: HY-182319

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Dehatrine

Dehatrine is a dibenzylisoquinoline alkaloid with antiplasmodial activity. Dehatrine can be found in the Indonesian medicinal plant Beilschmiedia madang. Dehatrine is applicable to malaria-related research.

For research use only. We do not sell to patients.

CAS No.: 19634-27-6
Formula: C₃₇H₃₈N₂O₆
Molecular Weight:606.71

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dehatrine Chemical Structure

CAS No.: 19634-27-6

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Biological Activity

Description

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In Vitro

Dehatrine potently inhibits the proliferation of Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain K1 in human red blood cells, with an IC₅₀ of 0.17 μM and an IC₉₀ of 3.6 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 19634-27-6
Molecular Weight 606.71
Formula C₃₇H₃₈N₂O₆
SMILES

COC1=C2C3=C(CCN([C@]3([H])CC4=CC=C(OC)C(OC5=CC=C(CC6=NCCC7=CC(OC)=C(O2)C=C67)C=C5)=C4)C)C=C1OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kitagawa I, et al. Dehatrine, an antimalarial bisbenzylisoquinoline alkaloid from the Indonesian medicinal plant Beilschmiedia madang, isolated as a mixture of two rotational isomers. Chem Pharm Bull (Tokyo). 1993;41(5):997-999. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Dehatrine

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Dehatrine Related Classifications

HY-182319 Related Classifications