3'-Azido-3'-deoxyadenosine
Based on 1 Customer Validation
3'-Azido-3'-deoxyadenosine is a purine nucleoside analog. 3'-Azido-3'-deoxyadenosine acts as a click chemistry reagent bearing an Azide group, which undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an Alkyne group. 3'-Azido-3'-deoxyadenosine also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- 純度: 98.44%
- CAS 番号: 58699-62-0
- 分子式: C10H12N8O3
- 分子量:292.25
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
3'-Azido-3'-deoxyadenosine can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 58699-62-0
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性状 Solid
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分子量 292.25
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分子式 C10H12N8O3
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Color White to off-white
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SMILES
OC[C@H]1O[C@@H](N(C=N2)C3=C2C(N)=NC=N3)[C@H](O)[C@@H]1N=[N+]=[N-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (427.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Robak T, et al. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-3388. [Content Brief]
[2]. Steger J, et al. Efficient access to nonhydrolyzable initiator tRNA based on the synthesis of 3'-azido-3'-deoxyadenosine RNA. Angew Chem Int Ed Engl. 2010 Oct 4;49(41):7470-2. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4217 mL | 17.1086 mL | 34.2173 mL | 85.5432 mL |
| 5 mM | 0.6843 mL | 3.4217 mL | 6.8435 mL | 17.1086 mL | |
| 10 mM | 0.3422 mL | 1.7109 mL | 3.4217 mL | 8.5543 mL | |
| 15 mM | 0.2281 mL | 1.1406 mL | 2.2812 mL | 5.7029 mL | |
| 20 mM | 0.1711 mL | 0.8554 mL | 1.7109 mL | 4.2772 mL | |
| 25 mM | 0.1369 mL | 0.6843 mL | 1.3687 mL | 3.4217 mL | |
| 30 mM | 0.1141 mL | 0.5703 mL | 1.1406 mL | 2.8514 mL | |
| 40 mM | 0.0855 mL | 0.4277 mL | 0.8554 mL | 2.1386 mL | |
| 50 mM | 0.0684 mL | 0.3422 mL | 0.6843 mL | 1.7109 mL | |
| 60 mM | 0.0570 mL | 0.2851 mL | 0.5703 mL | 1.4257 mL | |
| 80 mM | 0.0428 mL | 0.2139 mL | 0.4277 mL | 1.0693 mL | |
| 100 mM | 0.0342 mL | 0.1711 mL | 0.3422 mL | 0.8554 mL |
3'-Azido-3'-deoxyadenosine 関連分類
HY-131802 関連分類
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