1. Anti-infection
  2. Bacterial
  3. Furanone C-30

Furanone C-30 

Cat. No.: HY-131011
Handling Instructions

Furanone C-30 is a quorum sensing inhibitor. Furanone C-30 can effectively inhibit bacterial biofilm formation by S. mutans and its luxSmutant strain.

For research use only. We do not sell to patients.

Furanone C-30 Chemical Structure

Furanone C-30 Chemical Structure

CAS No. : 247167-54-0

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Description

Furanone C-30 is a quorum sensing inhibitor. Furanone C-30 can effectively inhibit bacterial biofilm formation by S. mutans and its luxSmutant strain[1].

IC50 & Target

Bacterial biofilm[1]

In Vitro

The difference in the OD590 values is statistically significant at concentrations of 2.0 μg/mL and 4.0 μg/mL compared with the control group. Furanone C-30 (2.0 μg/mL and 4.0 μg/mL) can inhibit biofilm formation by S. mutans and its luxS mutant strain, although it does not affect the bacterial growth rate itself[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Streptococcus mutans UA159 and its luxS mutant strain
Concentration: 0.0, 2.0 and 4.0 μg/mL
Incubation Time: 24 hours
Result: When 2.0 μg/mL was added, the OD590 values for S. mutans and its luxS mutant strain decreased by 42.7% and 40.8%, respectively. When the concentration was increased to 4.0 μg/mL, a decrease of 61.5% and 60.3%, respectively.
Molecular Weight

253.88

Formula

C₅H₂Br₂O₂

CAS No.

247167-54-0

SMILES

O=C(C=C/1Br)OC1=C/Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Furanone C-30Furanone C30Furanone C 30BacterialInhibitorinhibitorinhibit

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Furanone C-30
Cat. No.:
HY-131011
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