ZN148
ZN148 is a zinc-chelating synthetic metallo-β-lactamase (MBL) inhibitor which attenuates MBL-mediated carbapenem resistance. ZN148 can restore the in vitro clinical susceptibility to carbapenems in >98% of a large international collection of MBL-producing clinical Enterobacterales strains. ZN148 can be utilized in research on anti MBL-producing bacteria.
For research use only. We do not sell to patients.
- CAS No.: 2190527-04-7
- Formula: C26H33N5O6
- Molecular Weight:511.57
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Beta-lactamase Isoforms
More
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>100 μM
Compound: S29
|
Cytotoxicity against human HepG2 cells incubated for 24 hrs by AlamarBlue-based assay
Cytotoxicity against human HepG2 cells incubated for 24 hrs by AlamarBlue-based assay
|
[PMID: 37360393] |
Chemical Information
-
CAS No. 2190527-04-7
-
Molecular Weight 511.57
-
Formula C26H33N5O6
-
SMILES
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CN(C)C(C(C=N1)=CC=C1CN(CC2=CC=CC=N2)CC3=CC=CC=N3)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZN148 Related Classifications
HY-176565 Related Classifications
Powered by Bioz