Sarubicin B
Sarubicin B is an active product that can be isolated from the culture filtrate of a Streptomyces strain JA 2861. Sarubicin B is a quinone antibiotic that inhibit Gram-positive bacteria and not active against Gram-negative microorganisms.
For research use only. We do not sell to patients.
- CAS No.: 84745-01-7
- Formula: C13H10N2O4
- Molecular Weight:258.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 4T1 | IC50 |
7.6 μM
Compound: 2
|
Cytotoxicity against mouse 4T1 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
Cytotoxicity against mouse 4T1 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
|
[PMID: 35213166] |
| A549 | IC50 |
13.5 μM
Compound: 2
|
Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
|
[PMID: 35213166] |
| HCT-116 | IC50 |
14.8 μM
Compound: 2
|
Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
|
[PMID: 35213166] |
| HepG2 | IC50 |
6.3 μM
Compound: 2
|
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 72 hrs by CCK8 assay
|
[PMID: 35213166] |
Chemical Information
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CAS No. 84745-01-7
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Molecular Weight 258.23
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Formula C13H10N2O4
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SMILES
O=C(N)C(C1=O)=C(C(C2=C1C=CC=C2C(C)=O)=O)N
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Structure Classification
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Initial Source
streptomyces strain
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)