1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Nilofabicin

Nilofabicin (Synonyms: CG-400549)

Cat. No.: HY-111071
Handling Instructions

Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin.

For research use only. We do not sell to patients.

Nilofabicin Chemical Structure

Nilofabicin Chemical Structure

CAS No. : 934628-27-0

Size Price Stock Quantity
50 mg USD 240 In-stock
Estimated Time of Arrival: December 31
100 mg USD 400 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1].

Molecular Weight

340.44

Formula

C₁₉H₂₀N₂O₂S

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (293.74 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9374 mL 14.6869 mL 29.3738 mL
5 mM 0.5875 mL 2.9374 mL 5.8748 mL
10 mM 0.2937 mL 1.4687 mL 2.9374 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.34 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.34 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.34 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Nilofabicin
Cat. No.:
HY-111071
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