Nilofabicin (Standard)
Nilofabicin (Standard) is an analytical standard for Nilofabicin (HY-111071). This product is intended for research and analytical applications. Nilofabicin (CG-400549) is an anti-bacterialagent that targets FabI. Nilofabicin shows high selectivity for the genus Staphylococcus and weak activity against most Gram-negative bacteria. Nilofabicin inhibits bacterial fatty acid biosynthesis, blocks phospholipid synthesis, and disrupts the structure of bacterial cell membranes. Nilofabicin exhibits in vivo antibacterial efficacy in a mouse model of systemic Staphylococcus aureus infection. Nilofabicin can be used in studies related to bacterial infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 934628-27-0
- 分子式: C19H20N2O2S
- 分子量:340.44
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 934628-27-0
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分子量 340.44
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分子式 C19H20N2O2S
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SMILES
O=C1C=C(OCCC2=CC=CS2)C=CN1CC3=CC=CC(N)=C3C
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別名
CG-400549 (Standard)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Kim BY, et al. Solid state of CG-400549, a novel FabI inhibitor: characterization, dissolution, transformation. Archives of pharmacal research. 2011 May;34(5):775-9. [Content Brief]
[2]. Douglas EJA, et al. Novel antimicrobial strategies to treat multi-drug resistant Staphylococcus aureus infections. Microbial biotechnology. 2023 Jul;16(7):1456-1474. [Content Brief]
[3]. Wang J, et al. Inhibitors of fatty acid synthesis in prokaryotes and eukaryotes as anti-infective, anticancer and anti-obesity drugs. Future medicinal chemistry. 2012 Jun;4(9):1113-51. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Nilofabicin (Standard) 関連分類
HY-111071R 関連分類
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