2. Anti-infection
  3. Bacterial
  4. 2'-Amino-2'-deoxyguanosine

2'-Amino-2'-deoxyguanosine is a nucleoside antibiotic. 2'-Amino-2'-deoxyguanosine exhibits lethal activity against certain strains of Escherichia coli, with its antibacterial effect reversible by guanosine and other purine nucleosides. 2'-Amino-2'-deoxyguanosine can be used for the study of bacterial infection.

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2'-Amino-2'-deoxyguanosine

2'-Amino-2'-deoxyguanosine Chemical Structure

CAS No. : 60966-26-9

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2'-Amino-2'-deoxyguanosine Related Antibodies

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Description

2'-Amino-2'-deoxyguanosine is a nucleoside antibiotic. 2'-Amino-2'-deoxyguanosine exhibits lethal activity against certain strains of Escherichia coli, with its antibacterial effect reversible by guanosine and other purine nucleosides. 2'-Amino-2'-deoxyguanosine can be used for the study of bacterial infection[1].

Molecular Weight

282.26

Formula

C10H14N6O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](N)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (177.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5428 mL 17.7142 mL 35.4283 mL
5 mM 0.7086 mL 3.5428 mL 7.0857 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5428 mL 17.7142 mL 35.4283 mL 88.5708 mL
5 mM 0.7086 mL 3.5428 mL 7.0857 mL 17.7142 mL
10 mM 0.3543 mL 1.7714 mL 3.5428 mL 8.8571 mL
15 mM 0.2362 mL 1.1809 mL 2.3619 mL 5.9047 mL
20 mM 0.1771 mL 0.8857 mL 1.7714 mL 4.4285 mL
25 mM 0.1417 mL 0.7086 mL 1.4171 mL 3.5428 mL
30 mM 0.1181 mL 0.5905 mL 1.1809 mL 2.9524 mL
40 mM 0.0886 mL 0.4429 mL 0.8857 mL 2.2143 mL
50 mM 0.0709 mL 0.3543 mL 0.7086 mL 1.7714 mL
60 mM 0.0590 mL 0.2952 mL 0.5905 mL 1.4762 mL
80 mM 0.0443 mL 0.2214 mL 0.4429 mL 1.1071 mL
100 mM 0.0354 mL 0.1771 mL 0.3543 mL 0.8857 mL
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2'-Amino-2'-deoxyguanosine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2'-Amino-2'-deoxyguanosine60966-26-9BacterialEscherichia colibacterial infectionantibioticInhibitorinhibitorinhibit

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