H-L-Tyr(2-azidoethyl)-OH hydrochloride
Based on 1 Customer Validation
H-L-Tyr(2-azidoethyl)-OH hydrochloride is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH hydrochloride is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Purity : 99.88%
- CAS No.: 1567845-62-8
- Formula: C11H15ClN4O3
- Molecular Weight:286.71
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Storage:
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Biological Activity
Description
Chemical Information
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CAS No. 1567845-62-8
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Appearance Solid
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Molecular Weight 286.71
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Formula C11H15ClN4O3
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Color White to off-white
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SMILES
OC([C@@H](N)CC1=CC=C(C=C1)OCCN=[N+]=[N-])=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 11.67 mg/mL (40.70 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Maza JC, et al. Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations. Bioconjug Chem. 2015 Sep 16;26(9):1884-9. [Content Brief]
[2]. Tookmanian EM, et al. Azidoethoxyphenylalanine as a Vibrational Reporter and Click Chemistry Partner in Proteins. Chemistry. 2015 Dec 21;21(52):19096-103. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.4878 mL | 17.4392 mL | 34.8784 mL | 87.1961 mL |
| 5 mM | 0.6976 mL | 3.4878 mL | 6.9757 mL | 17.4392 mL | |
| 10 mM | 0.3488 mL | 1.7439 mL | 3.4878 mL | 8.7196 mL | |
| 15 mM | 0.2325 mL | 1.1626 mL | 2.3252 mL | 5.8131 mL | |
| 20 mM | 0.1744 mL | 0.8720 mL | 1.7439 mL | 4.3598 mL | |
| 25 mM | 0.1395 mL | 0.6976 mL | 1.3951 mL | 3.4878 mL | |
| 30 mM | 0.1163 mL | 0.5813 mL | 1.1626 mL | 2.9065 mL | |
| 40 mM | 0.0872 mL | 0.4360 mL | 0.8720 mL | 2.1799 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.