1567845-62-8
Chemical Structure
H-L-Tyr(2-azidoethyl)-OH hydrochloride
- CAS No.: 1567845-62-8
- Formula:C11H15ClN4O3
- Molecular Weight:286.71
IUPAC Name: (S)-2-amino-3-(4-(2-azidoethoxy)phenyl)propanoic acid hydrochloride
InChIKey: MBKGXPOLFHKIJE-PPHPATTJSA-N
SMILES: OC([C@@H](N)CC1=CC=C(C=C1)OCCN=[N+]=[N-])=O.Cl
Biological Activity: H-L-Tyr(2-azidoethyl)-OH hydrochloride is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH hydrochloride is a click chemistry reagent containing an azide group[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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H-L-Tyr(2-azidoethyl)-OH hydrochloride | 99.88% | H-L-Tyr(2-azidoethyl)-OH hydrochloride is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH hydrochloride is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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- [1]. Maza JC, et al. Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations. Bioconjug Chem. 2015 Sep 16;26(9):1884-9. [Content Brief]
- [2]. Tookmanian EM, et al. Azidoethoxyphenylalanine as a Vibrational Reporter and Click Chemistry Partner in Proteins. Chemistry. 2015 Dec 21;21(52):19096-103. [Content Brief]