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Cat. No.: HY-170830

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Mtb against-1

Mtb against-1 (compound 17af) is an inhibitor of Mycobacterium tuberculosis, with IC₉₀ values of 1.2 μM and 0.9 μM for the wild-type and LepB low-deformation strains, respectively.

For research use only. We do not sell to patients.

Formula: C₂₃H₁₉F₃N₄O₂S
Molecular Weight:472.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Mtb against-1 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Mtb against-1 (compound 17af) is an inhibitor of Mycobacterium tuberculosis, with IC₉₀ values of 1.2 μM and 0.9 μM for the wild-type and LepB low-deformation strains, respectively^[1].

IC₅₀ & Target

Mtb^[1]

Chemical Information

Molecular Weight 472.48
Formula C₂₃H₁₉F₃N₄O₂S
SMILES

NC1=C(C(NC(C2=CC=CC=C2)C)=O)SC3=C1C(C(F)(F)F)=CC(C4=CC=C(OC)N=C4)=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lynde BE, et al. Novel 3-Aminothieno[2,3-b]pyridine-2-carboxamides with Activity against Mycobacterium tuberculosis. ACS Med Chem Lett. 2025 Jan 3;16(2):241-249. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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