1. Anti-infection
  2. Reverse Transcriptase
    HIV
    HBV
    HCV
  3. FNC-TP trisodium

FNC-TP trisodium 

Cat. No.: HY-139262A
Handling Instructions

FNC-TP trisodium is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV.

For research use only. We do not sell to patients.

FNC-TP trisodium Chemical Structure

FNC-TP trisodium Chemical Structure

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Description

FNC-TP trisodium is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV[1].

IC50 & Target

reverse transcriptase[1]
HIV[1]
HBV[1]
HCV[1]

In Vitro

FNC (0.1-10 nM; 24-240 h) is found mainly to accumulate in these HIV-1 target cells, and the retention of FNC-TP is 2-4 times higher than in other types of cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

FNC (1-6 mg/kg; a single p.o.) could enter rhesus macaque PBMCs and form the active nucleoside triphosphate FNC-TP[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

592.11

Formula

C₉H₁₁FN₆Na₃O₁₃P₃

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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FNC-TP trisodium
Cat. No.:
HY-139262A
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