Polyketide synthase 13-IN-3
Polyketide synthase 13-IN-3 (compound 41) is a polyketide synthase 13 inhibitor,with a MIC of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv.
For research use only. We do not sell to patients.
- CAS No.: 2221801-50-7
- Formula: C21H19NO4
- Molecular Weight:349.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
MIC: 0.0625-0.125 μg/mL (M. tuberculosis strain H37Rv)[1].
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>50 μg/mL
Compound: 41
|
Cytotoxicity against human HEK293 cells after 48 hrs by CellTiter96 AQueous one solution assay
Cytotoxicity against human HEK293 cells after 48 hrs by CellTiter96 AQueous one solution assay
|
[PMID: 29328655] |
| HFL1 | IC50 |
>50 μg/mL
Compound: 41
|
Cytotoxicity against HFL1 cells after 48 hrs by CellTiter96 AQueous one solution assay
Cytotoxicity against HFL1 cells after 48 hrs by CellTiter96 AQueous one solution assay
|
[PMID: 29328655] |
| MRC5 | IC50 |
>50 μg/mL
Compound: 41
|
Cytotoxicity against human MRC5 cells after 48 hrs by CellTiter96 AQueous one solution assay
Cytotoxicity against human MRC5 cells after 48 hrs by CellTiter96 AQueous one solution assay
|
[PMID: 29328655] |
| Vero | IC50 |
4 μg/mL
Compound: 41
|
Cytotoxicity against African green monkey Vero cells after 72 hrs by MABA
Cytotoxicity against African green monkey Vero cells after 72 hrs by MABA
|
[PMID: 29328655] |
Chemical Information
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CAS No. 2221801-50-7
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Molecular Weight 349.38
-
Formula C21H19NO4
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SMILES
O=C1OC2=C(C3=C1C4=C(CN5CCCCC5)C(O)=CC=C4O3)C=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)