Diclosulam
Based on 1 Customer Validation
Diclosulam (XDE 564) is a herbicide with a Ki value of ＜32 nM and MIC and MIC50 values of 6.25, 1.40, 12.5 and 3.01 μM against CBS10913 and CBS12373 strains, respectively.
For research use only. We do not sell to patients.
- Purity: 98.20%
- CAS No.: 145701-21-9
- Formula: C13H10Cl2FN5O3S
- Molecular Weight:406.22
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Anti-Infection Compound Library
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Antibacterial Compound Library
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Biological Activity
Chemical Information
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CAS No. 145701-21-9
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Appearance Solid
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Molecular Weight 406.22
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Formula C13H10Cl2FN5O3S
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SMILES
O=S(C1=NN2C(OCC)=NC(F)=CC2=N1)(NC3=C(Cl)C=CC=C3Cl)=O
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Synonyms
XDE 564
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (246.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4617 mL | 12.3086 mL | 24.6172 mL | 61.5430 mL |
| 5 mM | 0.4923 mL | 2.4617 mL | 4.9234 mL | 12.3086 mL | |
| 10 mM | 0.2462 mL | 1.2309 mL | 2.4617 mL | 6.1543 mL | |
| 15 mM | 0.1641 mL | 0.8206 mL | 1.6411 mL | 4.1029 mL | |
| 20 mM | 0.1231 mL | 0.6154 mL | 1.2309 mL | 3.0772 mL | |
| 25 mM | 0.0985 mL | 0.4923 mL | 0.9847 mL | 2.4617 mL | |
| 30 mM | 0.0821 mL | 0.4103 mL | 0.8206 mL | 2.0514 mL | |
| 40 mM | 0.0615 mL | 0.3077 mL | 0.6154 mL | 1.5386 mL | |
| 50 mM | 0.0492 mL | 0.2462 mL | 0.4923 mL | 1.2309 mL | |
| 60 mM | 0.0410 mL | 0.2051 mL | 0.4103 mL | 1.0257 mL | |
| 80 mM | 0.0308 mL | 0.1539 mL | 0.3077 mL | 0.7693 mL | |
| 100 mM | 0.0246 mL | 0.1231 mL | 0.2462 mL | 0.6154 mL |
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