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Cat. No.: HY-N19842

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Neomethymycin

Neomethymycin (Compound5) is a 12-membered ring macrolide natural product. Neomethymycin can be found in engineered Streptomyces venezuelae ATCC 15439 strain DHS2001, where it forms via biotransformation of 10-deoxymethyonolide.

For research use only. We do not sell to patients.

CAS No.: 497-73-4
Formula: C₂₅H₄₃NO₇
Molecular Weight:469.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Neomethymycin Chemical Structure

CAS No.: 497-73-4

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

Microbial Metabolite

All Endogenous Metabolite Isoforms :

In Vitro

Neomethymycin (sufficient time to yield product; assessed over culture growth phase) is predominately produced alongside methymycin via biotransformation of 10-deoxymethyonolide by pre-log phase cultures of Streptomyces venezuelae strain DHS2001, with a combined methymycin product yield of 66% (15% overall from (R)-Roche ester)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 497-73-4
Molecular Weight 469.61
Formula C₂₅H₄₃NO₇
SMILES

O[C@H]([C@H](C[C@H](O1)C)N(C)C)[C@@H]1O[C@@H]2[C@H](C(O[C@]([C@@H](/C=C/C([C@@H](C[C@@H]2C)C)=O)C)([H])[C@H](O)C)=O)C
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces venezuelae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hansen DA, et al. Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin. J Am Chem Soc. 2013;135(30):11232-11238. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Neomethymycin

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Neomethymycin Related Classifications

HY-N19842 Related Classifications